40191-32-0
40191-32-0 結(jié)構(gòu)式
基本信息
四氫吡喃-4-酰氯
四氫吡喃-4-甲酰氯
4-氫吡喃-4-甲酰氯
四氫-2H-吡喃-4-羰基氯
四氫-2H-吡喃-4-碳酰氯
四氫-2H-吡喃-4-甲酰氯
四氫-2H-吡喃-4-羰酰氯
四氫-2H-吡喃-4-羰基氯化物
Trahydr-opyran-4-carbonyl chloride
4-(Chlorocarbonyl)tetrahydro-2H-pyran
Tetrahydro-pyran-4-carbonyl chloride
Tetrahydro-2H-pyrane-4-carbonylchloride
TETRAHYDRO-2H-PYRAN-4-CARBONYL CHLORIDE
2H-Pyran-4-carbonyl chloride, tetrahydro-
Tetrahydro-2H-pyran-4-carbonyl chloride 97%
tetrahydro-2H-pyran-4-carbonyl chloride
Tetrahydro-2H-pyran-4-carbonyl chloride ,97%
物理化學(xué)性質(zhì)
安全數(shù)據(jù)
制備方法
5337-03-1
40191-32-0
在50 mL三口圓底燒瓶中，依次加入6.85 g (52.6 mmol)四氫吡喃-4-甲酸、9.79 g (82.3 mmol)亞硫酰氯和10 mL甲苯，裝配攪拌子、溫度計(jì)及回流冷凝管。將反應(yīng)體系置于80℃油浴中，持續(xù)攪拌反應(yīng)1.5小時(shí)。反應(yīng)結(jié)束后，通過減壓蒸餾除去溶劑及過量亞硫酰氯，得到7.81 g (產(chǎn)率100%)四氫吡喃-4-甲酰氯，產(chǎn)物為淡褐色液體。產(chǎn)物表征數(shù)據(jù)如下：1H-NMR (CDCl3, δ/ppm): 1.79-1.93 (2H, m), 1.99-2.06 (2H, m), 2.91-3.00 (1H, m), 3.40-3.49 (2H, m), 3.97-4.03 (2H, m); CI-MS (m/z): 131 [M+1]+。
參考文獻(xiàn)：
[1] Patent: US2008/306287, 2008, A1. Location in patent: Page/Page column 6
[2] Patent: WO2008/71948, 2008, A2. Location in patent: Page/Page column 11-12
[3] Helvetica Chimica Acta, 1997, vol. 80, # 5, p. 1528 - 1551
[4] Journal of the Chemical Society, 1930, p. 2525,2529
[5] Chemical and Pharmaceutical Bulletin, 1987, vol. 35, # 6, p. 2426 - 2436
| 報(bào)價(jià)日期 | 產(chǎn)品編號(hào) | 產(chǎn)品名稱 | CAS號(hào) | 包裝 | 價(jià)格 |
| 2025/05/22 | T3890 | 四氫-2H-吡喃-4-羰基氯 Tetrahydro-2H-pyran-4-carbonyl Chloride | 40191-32-0 | 1g | 120元 |
| 2025/05/22 | T3890 | 四氫-2H-吡喃-4-羰基氯 Tetrahydro-2H-pyran-4-carbonyl Chloride | 40191-32-0 | 5g | 335元 |
| 2017/11/01 | CC29902CB | 四氫吡喃-4-甲酰氯 tetrahydro-2H-pyran-4-carbonyl chloride | 40191-32-0 | 250MG | 654元 |