(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate
CAS-Nr.
23735-43-5
Englisch Name:
(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate
Synonyma:
(S)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate;(S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL TOSYLATE;Travoprost Impurity 51;(S)-O-ISOPROPYLIDENE GLYCEROL TOSYLATE;L-α,β-Isopropylideneglycerol-γ-tosylate;(S)-3-TOSYLOXY-1,2-PROPANEDIOL ACETONIDE;(S)-3-Toxyloxy-1,2-propanediol acetonide;2,3-ISOPROPYLIDENE-SN-GLYCEROL 1-TOSYLATE;(S)-1-O-tosyl-2,3-O-isopropylideneglycerol;(2S)-1-O-Tosyl-2-O,3-O-isopropylideneglycerol
CBNumber:
CB6164890
Summenformel:
C13H18O5S
Molgewicht:
286.34
MOL-Datei:
23735-43-5.mol
(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Eigenschaften
Schmelzpunkt:
29-31 °C
alpha
4.2 º (c=10, abs.alcohol)
Siedepunkt:
398.71°C (rough estimate)
Dichte
1.208 g/mL at 25 °C(lit.)
Brechungsindex
n 20/D 1.506(lit.)
Flammpunkt:
>230 °F
storage temp.
Inert atmosphere,2-8°C
Aggregatzustand
powder to lump to clear liquid
Farbe
White or Colorless to Light yellow
Optische Rotation
[α]26/D +7.5°, c = 2% in DMF
BRN
89799
InChI
InChI=1/C13H18O5S/c1-10-4-6-12(7-5-10)19(14,15)17-9-11-8-16-13(2,3)18-11/h4-7,11H,8-9H2,1-3H3/t11-/s3
InChIKey
SRKDUHUULIWXFT-LBPXTSNRNA-N
SMILES
C1(C=CC(C)=CC=1)S(=O)(=O)OC[C@@H]1COC(C)(C)O1 |&1:12,r|
CAS Datenbank
23735-43-5(CAS DataBase Reference)
(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Chemische Eigenschaften,Einsatz,Produktion Methoden
R-S?tze Betriebsanweisung:
R36/37/38:Reizt die Augen, die Atmungsorgane und die Haut.
S-S?tze Betriebsanweisung:
S26:Bei Berührung mit den Augen sofort gründlich mit Wasser abspülen und Arzt konsultieren.
S36:DE: Bei der Arbeit geeignete Schutzkleidung tragen.
S37/39:Bei der Arbeit geeignete Schutzhandschuhe und Schutzbrille/Gesichtsschutz tragen.
Chemische Eigenschaften
white to light yellow crystal powde
Verwenden
(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate has been used as a reactant for the synthesis of 16-(3-trifluoromethyl)phenoxy PGF2α analog travoprost (T715600) which has potent topical ocular activity. (S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p-Toluenesulfonate has also been used for the preparation of p38 mitogen activated protein (MAP) kinase inhibitors.
(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Upstream-Materialien And Downstream Produkte
Upstream-Materialien
Downstream Produkte
(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.
Global( 176)Lieferanten
Americas 1
Belgium 2
China 113
Europe 1
France 1
Germany 5
India 9
Japan 3
Slovakia 2
South Korea 1
Switzerland 2
The Netherlands 1
United Kingdom 8
United States 27
Global 176
23735-43-5()Verwandte Suche:
(S)-O-ISOPROPYLIDENE GLYCEROL TOSYLATE
(S)-(+)-2,2-DIMETHYL-4-(HYDROXYMETHYL)-1,3-DIOXOLANE-P-TOLUENESULFONATE
(S)-2,2-DIMETHYL-4-(HYDROXYMETHYL)-1,3-DIOXOLANE-P-TOLUENESULFONATE
(S)-(+)-2,2-DIMETHYL-4-(HYDROXYMETHYL)-1,3-DIOXOLANE-P-TOLUENSULFONATE
(S)-(+)-2,2-DIMETHYL-1,3-DIOXOLAN-4-YLMETHYL P-TOLUENESULFONATE
(S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL-4-METHYLBENZENESULFONATE
2,3-ISOPROPYLIDENE-SN-GLYCEROL 1-TOSYLATE
2,2-DIMETHYL-4(S)-4-(P-TOLYLSULFONYL)METHYL-1,3-DIOXALANE
1,3-DIOXOLANE-4-METHANOL, 2,2-DIMETHYL-, 4-METHYLBENZENESULFONATE, (4S)-
L-α,β-Isopropylideneglycerol-γ-tosylate
(S)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-toluenesulphonate
(S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL TOLUENE-4-SULFONATE
(S)-(+)-2,2-DIMETHYL-1,3-DIOXOLANE-4-YLMETHYL P-TOLUENESULFONATE
(S)-1,2-O-ISOPROPYLIDENEGLYCEROL-3-TOLUENESULFONATE
(S)-3-TOSYLOXY-1,2-PROPANEDIOL ACETONIDE
(S)-2,2-Dimethyl-1,3-dioxolane-4-methanol p-toluenesulfonate
(S)-3-Toxyloxy-1,2-propanediol acetonide
(s)-2,2-dimethyl-1,3-dioxolane-4-methyl p-toluenesulfonate
(S)-(+)-2,2-Dimethyl-1,3-dioxolane-4-methanol 4-toluenesulfo
2,3-Isopropylidene-sn-glycerol 1-tosylate, (S)-2,2-Dimethyl-1,3-dioxolane-4-methyl p-toluenesulfonate, L-α,β-Isopropylideneglycerol-γ-tosylate
2,3-Isopropylidene-sn-glycerol 1-tosylate, L-α,β-Isopropylideneglycerol-γ-tosylate
(2S)-1-O-Tosyl-2-O,3-O-isopropylideneglycerol
4-Methylbenzenesulfonic acid (S)-2,2-dimethyl-1,3-dioxolane-4α-ylmethyl ester
p-Toluenesulfonic acid [(S)-2,2-dimethyl-1,3-dioxolane-4α-yl]methyl ester
p-Toluenesulfonic acid [S,(+)]-2,2-dimethyl-1,3-dioxolan-4-ylmethyl ester
p-Toluenesulfonic acid [S,(+)]-2,2-dimethyl-1,3-dioxolane-4-ylmethyl ester
(S)-(+)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-toluenesulfonate,97%
L-ALPHA,BETA-ISOPROPYLIDENEGLYCEROL-GAMMA-TOSYLATE
L-(+)-1,2-ISOPROPYLIDENEGLYCEROL 3-(P-TOLUENESULFONATE)
(S)-(+)-2,2-Dimethyl-4-(hydroxymethyl)-1,3-dioxolane-p-tolue...
(S)-(2,2-dimethyl-1,3-dioxalan-4-yl)methyl-4-methylbenzenesulfonate
Travoprost Impurity 51
1,3-Dioxolane-4-methanol, 2,2-dimethyl-, 4-(4-methylbenzenesulfonate), (4S)-
(S)-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethylp-Toluenesulfonate>
(4S)-2,2-dimethyl-4-(4-toluenesulphonyloxymethyl)-1,3-dioxolane
(S)-(2,2-Dimethyl-1,3-dioxolan-4-yl)methyl 4-methylbenzenesulfonate
(S)-2,2-DIMETHYL-1,3-DIOXOLANE-4-METHANOL TOSYLATE
(S)-1-O-tosyl-2,3-O-isopropylideneglycerol
(S )-(+)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl p -toluenesulfonate
23735-43-5
Asymmetric Synthesis
Organic Building Blocks
Protected Alcohols
Dioxolanes
Chiral Building Blocks
Dioxanes & Dioxolanes
Glycidyl Compounds, etc. (Chiral)
chiral
Chiral Building Blocks
Dioxanes & Dioxolanes
Dioxolanes
Glycidyl Compounds, etc. (Chiral)
Synthetic Organic Chemistry
ADVANCED INT.