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Micheliolide

Micheliolide Struktur
68370-47-8
CAS-Nr.
68370-47-8
Englisch Name:
Micheliolide
Synonyma:
CS-1321;Mecheliolide;Micheliolide;Micheliolide, BR;Micheliolide 68370-47-8;Micheliolide, 10 mM in DMSO;Nuclear factor-κB,NF-κB,inhibit,Micheliolide,Nuclear factor-kappaB,Inhibitor;(3aS)-3aβ,4,5,7,8,9,9aβ,9bα-Octahydro-9β-hydroxy-6,9-dimethyl-3-methyleneazuleno[4,5-b]furan-2(3H)-one;(3aS,9R,9aS,9bS)-9-hydroxy-6,9-dimethyl-3-methylidene-4,5,7,8,9a,9b-hexahydro-3aH-azuleno[4,5-b]furan-2-one;Azuleno[4,5-b]furan-2(3H)-one, 3a,4,5,7,8,9,9a,9b-octahydro-9-hydroxy-6,9-dimethyl-3-methylene-, (3aS,9R,9aS,9bS)-
CBNumber:
CB42339810
Summenformel:
C15H20O3
Molgewicht:
248.32
MOL-Datei:
68370-47-8.mol

Micheliolide Eigenschaften

Schmelzpunkt:
131-133 °C
Siedepunkt:
426.1±45.0 °C(Predicted)
Dichte
1.17±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
L?slichkeit
Chloroform (Slightly), Methanol (Slightly)
Aggregatzustand
Solid
pka
14.65±0.40(Predicted)
Farbe
Off-White
InChI
InChI=1S/C15H20O3/c1-8-4-5-11-9(2)14(16)18-13(11)12-10(8)6-7-15(12,3)17/h11-13,17H,2,4-7H2,1,3H3/t11-,12-,13-,15+/m0/s1
InChIKey
RDJAFOWISVMOJY-PWNZVWSESA-N
SMILES
O1C(=O)C(=C)[C@]2([H])CCC(C)=C3[C@@]([H])([C@@]12[H])[C@@](O)(C)CC3

Sicherheit

Micheliolide Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

Micheliolide, a sesquiterpene lactone is used in the inhibition of resistant acute leukemic cells. Selectively targets cancer stem and progenitor cells.

Source

Micheliolide (MCL) is a potentially stable sesquiterpene lactone, which can be isolated from Magnolia grandiflora L., Michelia champaca L., and Michelia compressa (Maxim.) Sarg. MCL and its Michael adduct dimethylaminomicheliolide (DMAMCL) display significant cytotoxicity against tumours. MCL is known to be firstly isolated by Ogura, Cordell from Michelia compressa (Maxim.) Sarg. as a cytotoxic active component. MCL is also a main biologically active constituent of Michelia champaca L., Magnolia grandiflora L., and Tanacetum parthenium Sch. Bip., Anthemis scrobicularis Yavin, and Michelia compressa (Maxim.) Sarg[1].
(3aS)-3aβ,4,5,7,8,9,9aβ,9bα-Octahydro-9β-hydroxy-6,9-dimethyl-3-methyleneazuleno[4,5-b]furan-2(3H)-one  

Micheliolide Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

Micheliolide Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 117)Lieferanten
Firmenname Telefon E-Mail Land Produktkatalog Edge Rate
Accendatech Co., Ltd.
+8613132578992
 yunhao.liu@accendatech.com China 251 58
Shanghai Zheyan Biotech Co., Ltd. 		18017610038
zheyansh@163.com CHINA 3619 58
Chengdu Greenpure Biopharma CO.,Ltd 		18283602253; +8618283602253
 jancyzheng@gcgreenpure.com China 954 58
Chengdu GLP biotechnology Co Ltd 		028-87075086 13350802083
 scglp@glp-china.com CHINA 1824 58
Chengdu Biopurify Phytochemicals Ltd. 		+86-28-82633860; +8618080483897
 sales@biopurify.com China 3751 58
NanJing Spring & Autumn Biological Engineering CO., LTD. 		+8613815430202
 sale02@cqherb.com CHINA 376 58
career henan chemical co 		+86-0371-86658258 +8613203830695
 factory@coreychem.com China 29804 58
Wuhan ChemNorm Biotech Co.,Ltd. 		+86-27-8439 4403 18971486879
 sales@chemnorm.com CHINA 2935 58
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354
 marketing@targetmol.com United States 32376 58
ANHUI WITOP BIOTECH CO., LTD 		+8615255079626
 eric@witopchemical.com China 23541 58

68370-47-8()Verwandte Suche:

  • (3aS)-3aβ,4,5,7,8,9,9aβ,9bα-Octahydro-9β-hydroxy-6,9-dimethyl-3-methyleneazuleno[4,5-b]furan-2(3H)-one
  • Micheliolide
  • [3aS-(3aalpha,9alpha,9aalpha,9bbeta)]-3a,4,5,7,8,9,9a,9b-Octahydro-9-hydroxy-6,9-dimethyl-3-methylene-azuleno[4,5-b]furan-2(3H)-one
  • Micheliolide, BR
  • CS-1321
  • Micheliolide 68370-47-8
  • Mecheliolide
  • Azuleno[4,5-b]furan-2(3H)-one, 3a,4,5,7,8,9,9a,9b-octahydro-9-hydroxy-6,9-dimethyl-3-methylene-, (3aS,9R,9aS,9bS)-
  • (3aS,9R,9aS,9bS)-9-hydroxy-6,9-dimethyl-3-methylidene-4,5,7,8,9a,9b-hexahydro-3aH-azuleno[4,5-b]furan-2-one
  • Nuclear factor-κB,NF-κB,inhibit,Micheliolide,Nuclear factor-kappaB,Inhibitor
  • Micheliolide, 10 mM in DMSO
  • 68370-47-8
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