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2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol

2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol Struktur
1204975-42-7
CAS-Nr.
1204975-42-7
Englisch Name:
2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol
Synonyma:
LEQ-506;NVP-LEQ506;LEQ506, 10 mM in DMSO;LEQ-506,Inhibitor,LEQ 506,Smo,LEQ506,Smoothened,inhibit;(R)-2-(5-(4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methylpiperazin-1-yl)pyrazin-2-yl)propan-2-ol;2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol;2-Pyrazinemethanol, 5-[(2R)-4-[4,5-dimethyl-6-(phenylmethyl)-3-pyridazinyl]-2-methyl-1-piperazinyl]-α,α-dimethyl-;2-[(R)-4-(6-benzyl-4,5-dimethyl-pyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl-5'-yl]-propan-2-ol
CBNumber:
CB23138265
Summenformel:
C25H32N6O
Molgewicht:
432.56
MOL-Datei:
1204975-42-7.mol

2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol Eigenschaften

Siedepunkt:
685.4±55.0 °C(Predicted)
Dichte
1.170±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
L?slichkeit
DMSO : ≥ 100 mg/mL (231.18 mM)
pka
12.84±0.29(Predicted)
Aggregatzustand
Solid
Farbe
White to yellow

Sicherheit

2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol Chemische Eigenschaften,Einsatz,Produktion Methoden

Verwenden

LEQ506, is a second-generation inhibitor of smoothened (Smo) with IC50s of 2 and 4 nM in human and mouse, respectively.

2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol Upstream-Materialien And Downstream Produkte

Upstream-Materialien

Downstream Produkte

2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol Anbieter Lieferant Produzent Hersteller Vertrieb H?ndler.

Global( 24)Lieferanten
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TargetMol Chemicals Inc. 		+17819995354
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TargetMol Chemicals Inc.
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Aladdin Scientific
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Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627
 info@efebio.com China 9803 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 17801761073
 3193328036@qq.com China 29763 68
Nanjing KaiMubo Pharmaceutical Co., Ltd. 025-66162170
China 7181 55
Nanjing Asfam Pharmaceutical Technology Co., Ltd. 025-58867862 18751812725
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ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767
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Shanghai hongqu biomedical technology co. LTD 88888888888
 hongquchem@qq.com China 5132 58
Shanghai Botuo Biotechnology Co., LTD 16621358918
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  • 2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol
  • 2-[(R)-4-(6-benzyl-4,5-dimethyl-pyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl-5'-yl]-propan-2-ol
  • NVP-LEQ506
  • LEQ-506
  • (R)-2-(5-(4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methylpiperazin-1-yl)pyrazin-2-yl)propan-2-ol
  • 2-Pyrazinemethanol, 5-[(2R)-4-[4,5-dimethyl-6-(phenylmethyl)-3-pyridazinyl]-2-methyl-1-piperazinyl]-α,α-dimethyl-
  • LEQ-506,Inhibitor,LEQ 506,Smo,LEQ506,Smoothened,inhibit
  • LEQ506, 10 mM in DMSO
  • 1204975-42-7
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