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ChemicalBook >> CAS DataBase List >>2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol

2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol

CAS No.
1204975-42-7
Chemical Name:
2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol
Synonyms
LEQ-506;NVP-LEQ506;LEQ506, 10 mM in DMSO;LEQ-506,Inhibitor,LEQ 506,Smo,LEQ506,Smoothened,inhibit;(R)-2-(5-(4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methylpiperazin-1-yl)pyrazin-2-yl)propan-2-ol;2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol;2-Pyrazinemethanol, 5-[(2R)-4-[4,5-dimethyl-6-(phenylmethyl)-3-pyridazinyl]-2-methyl-1-piperazinyl]-α,α-dimethyl-;2-[(R)-4-(6-benzyl-4,5-dimethyl-pyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl-5'-yl]-propan-2-ol
CBNumber:
CB23138265
Molecular Formula:
C25H32N6O
Molecular Weight:
432.56
MDL Number:
MFCD27987902
MOL File:
1204975-42-7.mol
MSDS File:
SDS
Last updated:2025-07-20 09:44:47

2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol Properties

Boiling point 685.4±55.0 °C(Predicted)
Density 1.170±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMSO : ≥ 100 mg/mL (231.18 mM)
pka 12.84±0.29(Predicted)
form Solid
color White to yellow
FDA UNII 6SJX1T5HJD

2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-0011636 LEQ506 98.27% 1204975-42-7 1mg $751 2021-12-16 Buy
ChemScene CS-0011636 LEQ506 98.27% 1204975-42-7 5mg $1202 2021-12-16 Buy
ChemScene CS-0011636 LEQ506 98.27% 1204975-42-7 10mg $1923 2021-12-16 Buy
Crysdot CD11332423 LEQ506 95% 1204975-42-7 250mg $1150 2021-12-16 Buy
Crysdot CD11332423 LEQ506 95% 1204975-42-7 50mg $450 2021-12-16 Buy
Product number Packaging Price Buy
CS-0011636 1mg $751 Buy
CS-0011636 5mg $1202 Buy
CS-0011636 10mg $1923 Buy
CD11332423 250mg $1150 Buy
CD11332423 50mg $450 Buy

2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol Chemical Properties,Uses,Production

Uses

LEQ506, is a second-generation inhibitor of smoothened (Smo) with IC50s of 2 and 4 nM in human and mouse, respectively.

2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol Preparation Products And Raw materials

Raw materials

Preparation Products

2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol Suppliers

Global( 25)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32376 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 38838 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9803 58
Beijing Solarbio Science & Tecnology Co., Ltd. 010-50973130 17801761073 3193328036@qq.com China 29762 68
Nanjing KaiMubo Pharmaceutical Co., Ltd. 025-66162170 China 7181 55
Nanjing Asfam Pharmaceutical Technology Co., Ltd. 025-58867862 18751812725 sales@ace-pharm.com China 1988 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Shanghai hongqu biomedical technology co. LTD 88888888888 hongquchem@qq.com China 5132 58
Shanghai Botuo Biotechnology Co., LTD 16621358918 botuopharma888@163.com China 9208 58

View Lastest Price from 2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
LEQ506 pictures 2025-07-20 LEQ506
1204975-42-7
 US $58.00-222.00 / mg 98.53% 10g TargetMol Chemicals Inc.
LEQ506 pictures 2025-07-15 LEQ506
1204975-42-7
 US $58.00-222.00 / mg 98.53% 10g TargetMol Chemicals Inc.
  • LEQ506 pictures
  • LEQ506
    1204975-42-7
  • US $58.00-222.00 / mg
  • 98.53%
  • TargetMol Chemicals Inc.
  • LEQ506 pictures
  • LEQ506
    1204975-42-7
  • US $58.00-222.00 / mg
  • 98.53%
  • TargetMol Chemicals Inc.

2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol Spectrum

2-[4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2]bipyrazinyl-5-yl]-propan-2-ol 2-[(R)-4-(6-benzyl-4,5-dimethyl-pyridazin-3-yl)-2-methyl-3,4,5,6-tetrahydro-2H-[1,2']bipyrazinyl-5'-yl]-propan-2-ol NVP-LEQ506 LEQ-506 (R)-2-(5-(4-(6-Benzyl-4,5-dimethylpyridazin-3-yl)-2-methylpiperazin-1-yl)pyrazin-2-yl)propan-2-ol 2-Pyrazinemethanol, 5-[(2R)-4-[4,5-dimethyl-6-(phenylmethyl)-3-pyridazinyl]-2-methyl-1-piperazinyl]-α,α-dimethyl- LEQ-506,Inhibitor,LEQ 506,Smo,LEQ506,Smoothened,inhibit LEQ506, 10 mM in DMSO 1204975-42-7