| Identification | More | [Name]
(5-Carboxypentyl)(triphenyl)phosphonium bromide | [CAS]
50889-29-7 | [Synonyms]
(5-CARBOXYPENTYL)TRIPHENYLPHOSPHONIUM BROMIDE
(5-CARBOXYAMYL)TRIPHENYLPHOSPHONIUM BROMIDE
5-carboxypentyltriphenylphosphonium bromide, 98 % | [Molecular Formula]
C24H26BrO2P | [MDL Number]
MFCD00055556 | [Molecular Weight]
457.34 | [MOL File]
50889-29-7.mol |
| Chemical Properties | Back Directory | [Appearance]
White Crystalline Solid | [Melting point ]
197-201 °C
| [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
Soluble in Chloroform and Methanol. | [form ]
Solid | [color ]
White to Off-White | [Sensitive ]
Hygroscopic | [InChI]
InChI=1S/C24H25O2P.BrH/c25-24(26)19-11-4-12-20-27(21-13-5-1-6-14-21,22-15-7-2-8-16-22)23-17-9-3-10-18-23;/h1-3,5-10,13-18H,4,11-12,19-20H2;1H | [InChIKey]
JUWYRPZTZSWLCY-UHFFFAOYSA-N | [SMILES]
[P+](CCCCCC(=O)O)(C1C=CC=CC=1)(C1=CC=CC=C1)C1C=CC=CC=1.[Br-] | [CAS DataBase Reference]
50889-29-7(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi,Xn | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S22:Do not breathe dust . | [WGK Germany ]
3
| [HS Code ]
2931599090 |
| Questions and Answers (Q&A) | Back Directory | [Uses]
(5-Carboxypentyl)(triphenyl)phosphonium bromide is used in medicine and as pharmaceutical intermediate. It is also employed as catalyst.
Reactant for:
- Preparation of inhibitor of protein tyrosine phosphatase 1B for treatment of diabetes and obesity.
- Synthesis of folate receptor-specific glycinamide ribonucleotide formyltransferase inhibitors with antitumor activity.
- Preparation of peptide nucleic acids (PNA) with high specific activity.
- Synthesis of roseophilin via Wittig/aldol methodology.
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