Benzenepropanoic acid, 3-fluoro-, Methyl ester synthesis
- Product Name:Benzenepropanoic acid, 3-fluoro-, Methyl ester
- CAS Number:425704-52-5
- Molecular formula:C10H11FO2
- Molecular Weight:182.19
67-56-1
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$9.00/25ml
458-45-7
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$22.00/250mg
425704-52-5
26 suppliers
$165.00/500mg
Yield:425704-52-5 98%
Reaction Conditions:
with sulfuric acid for 6 h;Reflux;
Steps:
3 -(3 -Fluorophenyl) propionic acid (5.00 g, 29.7 mmol) was dissolved in MeOH (50 mL) and H2SO4 (1 mL) was added. The reaction mixture was heated at reflux for 6 h and concentrated in vacuo to approximately 15 mL. EtOAc (100 mL) was added and the organic fraction was washed with 1 M aq Na2CC>3 (2 x 100 mL), dried (MgS04) and the solvents were removed in vacuo to give the title compound as a pale yellow oil (5.28 g, 98%) which used without further purification or characterization.
References:
WO2012/41817,2012,A1 Location in patent:Page/Page column 39
74325-03-4
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$25.00/1g
425704-52-5
26 suppliers
$165.00/500mg
103-26-4
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$6.00/25g
425704-52-5
26 suppliers
$165.00/500mg
87087-34-1
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inquiry
425704-52-5
26 suppliers
$165.00/500mg
456-48-4
406 suppliers
$9.00/25g
425704-52-5
26 suppliers
$165.00/500mg