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Carbohydrate Research

Carbohydrate Research

IF: 2.39
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A rapid synthesis of sphingosine from phytosphingosine

Published:30 June 2018 DOI: 10.1016/j.carres.2018.04.006 PMID: 29689448
Arumugam Sankar, I-Cheng Chen, Shun-Yuan Luo

Abstract

A simple and efficient protocol for the synthesis of a sphingosine starting from cost-effective phytosphingosine has been described. Two alternative synthetic pathway have been disclosed based on the use of two different kinds of protective groups for the protection of the amino group in the phytosphingosine. The protected phytosphingosine was subsequently transformed into sphingosine in 5 steps i.e. protection of the amine group, protection of 1,3-diol, leaving group insertion, elimination, and one-pot deprotection.

Substances (3)

Related products
Procduct Name CAS Molecular Formula Supplier Price
Phytosphingosine 554-62-1 C18H39NO3 278 suppliers $39.00-$941.22
D-ERYTHRO-SPHINGOSINE 123-78-4 C18H37NO2 249 suppliers $30.00-$1870.00
phytosphingosine 13552-11-9 C18H39NO3 97 suppliers Inquiry

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