午夜插插,噜噜噜影院,啪啪伊人网,欧美熟夫,景甜吻戏视频,男人强操性感蕾丝美女视频在线网站,日本美女跳舞视频

HistoneH3(monomethylK18)抗體,Rabbit Monoclonal HistoneH3(monomethylK18) Antibody
  • HistoneH3(monomethylK18)抗體,Rabbit Monoclonal HistoneH3(monomethylK18) Antibody
  • HistoneH3(monomethylK18)抗體,Rabbit Monoclonal HistoneH3(monomethylK18) Antibody
  • HistoneH3(monomethylK18)抗體,Rabbit Monoclonal HistoneH3(monomethylK18) Antibody

HistoneH3(monomethylK18)抗體;HistoneH3(monomethylK18) Antibody—艾普蒂

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 上海
更新日期 2025-05-29
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:HistoneH3(monomethylK18)抗體英文名稱:Rabbit Monoclonal HistoneH3(monomethylK18) Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 7874 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: HistoneH3(monomethylK18)
2025-05-29 HistoneH3(monomethylK18)抗體 Rabbit Monoclonal HistoneH3(monomethylK18) Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 7874 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應用

應用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHCIHC:1/100-1/200;IHF:1/50-1/200 Human,Mouse,Rat
ICC1/50-1/200 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa咨詢技術(shù) Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesH3 histone; HIST1H3A; Histone cluster 1, H3a; H3K18me1;;MonoMethyl-Histone H3 (K19)
WB Predicted band size15 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman,Mouse,Rat
ImmunogenA synthesized peptide derived from human Histone H3.1 around the methylation site of K19
FormulationPurified antibody in PBS with 0.05% sodium azide,0.05% BSA and 50% glycerol.

+ +

  •  

     

       Western blot analysis of Histone H3 (mono methyl K18) expression in HeLa cell lysate.    


  •  

     

       All lanes use the Antibody at 1:2k dilution for 1 hour at room temperature.    


  •  

     

       Immunohistochemical analysis of paraffin-embedded human liver, using Histone H3 (mono methyl K18) Antibody.    


           

參考文獻

以下是關(guān)于Histone H3 (monomethyl K18) 抗體的3篇參考文獻及其摘要內(nèi)容:

---

1. **文獻名稱**:*"Site-specific methylation of histone H3K18 promotes DNA damage response initiation"*

**作者**:Smith ER, et al.

**摘要**:該研究揭示了組蛋白H3第18位賴氨酸單甲基化(H3K18me1)在DNA損傷應答中的調(diào)控作用。通過開發(fā)特異性抗體,作者證明H3K18me1在DNA損傷位點富集,并促進ATM激酶介導的修復信號傳導。

2. **文獻名稱**:*"Dynamic regulation of histone H3K18 methylation during cell cycle progression"*

**作者**:Li B, et al.

**摘要**:本文利用H3K18me1特異性抗體,通過免疫熒光和ChIP-seq技術(shù),揭示了該修飾在細胞周期中的動態(tài)變化。研究發(fā)現(xiàn)H3K18me1在G1期顯著富集于異染色質(zhì)區(qū)域,可能參與維持基因組穩(wěn)定性。

3. **文獻名稱**:*"H3K18 monomethylation marks active enhancers in embryonic stem cells"*

**作者**:Zhao Y, et al.

**摘要**:該研究通過H3K18me1抗體結(jié)合染色質(zhì)分析,發(fā)現(xiàn)該修飾特異性地標記胚胎干細胞中的活躍增強子區(qū)域,并調(diào)控多能性相關(guān)基因的表達,提示其在細胞命運決定中的表觀遺傳功能。

---

注:以上文獻信息為示例性內(nèi)容,實際文獻需通過PubMed或?qū)W術(shù)數(shù)據(jù)庫檢索確認具體標題及作者。如需真實文獻,可搜索關(guān)鍵詞“H3K18me1 antibody”或“histone H3 monomethylation K18”獲取相關(guān)研究。

       

背景信息

The histone H3 monomethylated at lysine 18 (H3K18me1) antibody is a critical tool for studying epigenetic regulation linked to gene expression and chromatin dynamics. Histone H3. a core component of nucleosomes, undergoes post-translational modifications (PTMs) such as methylation, which influence DNA accessibility and transcriptional activity. Monomethylation at lysine 18 (K18) is a conserved mark associated with both active and repressive chromatin states, depending on cellular context. H3K18me1 has been implicated in regulating developmental genes, maintaining stem cell pluripotency, and modulating DNA damage response pathways. Dysregulation of this mark is observed in cancers, where altered H3K18me1 levels correlate with tumor progression and patient prognosis.

This antibody specifically recognizes the monomethylated form of H3K18. distinguishing it from unmethylated, dimethylated, or trimethylated states. It is commonly used in techniques like Western blotting, chromatin immunoprecipitation (ChIP), and immunofluorescence to map H3K18me1 distribution across genomes or assess its abundance in cellular models. Researchers validate its specificity using knockout controls or competitive peptides. Studies employing this antibody have shed light on how H3K18me1 interacts with chromatin modifiers (e.g., SETD6 methyltransferase) and readers to orchestrate transcriptional programs. Its application continues to advance understanding of epigenetic mechanisms in development, disease, and therapeutic targeting.

       
關(guān)鍵字: HistoneH3(monomethyl;HistoneH3(monomethyl;HistoneH3(monomethyl;

公司簡介

生物技術(shù)有限公司
成立日期 2024-07-02 (2年) 注冊資本 20萬人民幣
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 抗體,植物生物技術(shù),細胞培養(yǎng),蛋白組學 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 上海切爾齊生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊資本:20萬人民幣
  • 企業(yè)類型:有限責任公司(自然人投資或控股)
  • 主營產(chǎn)品:生物試劑
  • 公司地址:青浦
詢盤

HistoneH3(monomethylK18)抗體;HistoneH3(monomethylK18) Antibody—艾普蒂相關(guān)廠家報價

產(chǎn)品名稱 價格   公司名稱 報價日期
詢價
VIP1年
上海切爾齊生物科技有限公司
2025-05-23
詢價
VIP3年
維百奧(北京)生物科技有限公司
2025-08-01
¥1800
VIP1年
費雪(杭州)醫(yī)學研究有限公司
2025-07-28
內(nèi)容聲明:
以上所展示的信息由商家自行提供,內(nèi)容的真實性、準確性和合法性由發(fā)布商家負責。 商家發(fā)布價格指該商品的參考價格,并非原價,該價格可能隨著市場變化,或是由于您購買數(shù)量不同或所選規(guī)格不同而發(fā)生變化。最終成交價格,請咨詢商家,以實際成交價格為準。請意識到互聯(lián)網(wǎng)交易中的風險是客觀存在的
主頁 | 企業(yè)會員服務(wù) | 廣告業(yè)務(wù) | 聯(lián)系我們 | 舊版入口 | 中文MSDS | CAS Index | 常用化學品CAS列表 | 化工產(chǎn)品目錄 | 新產(chǎn)品列表 |投訴中心
Copyright ? 2008 ChemicalBook 京ICP備07040585號  京公海網(wǎng)安備110108000080號  All rights reserved.