Product Name：GB-6
CAS No.：2413262-74-3
Synonyms：靶向胃泌素釋放肽受體多肽
Catalog No.：220P108
Brand：Typeptide Biotech（肽研生物）
Description：GB-6是一種短線性肽，靶向胃泌素釋放肽受體(GRPR)多肽，是由6個氨基酸組成的多肽。GRPR 在胰腺癌中過度表達，基于 GB-6 的腫瘤選擇性和腫瘤特異積累特性，近紅外 (NIR) 熒光染料或放射性核素锝-99m (99mTc) 標記的 GB-6 可用做高對比度成像探針。GB-6 具有優(yōu)異體內(nèi)穩(wěn)定性，在 SW199 0皮下異種移植模型中，腫瘤與胰腺和腸道熒光信號比分別為 5.2 和 6.3。GB-6 能快速靶向腫瘤，精確描繪腫瘤邊界，具有廣闊應用前景。
GB-6 is a short peptide that targets the gastrin releasing peptide receptor (GRPR) polypeptide, consisting of 6 amino acids. GRPR is overexpressed in pancreatic cancer. Based on the tumor selectivity and tumor specific accumulation characteristics of GB-6, GB-6 labeled with near-infrared (NIR) fluorescent dye or radionuclide technetium-99m (99mTc) can be used as a high contrast imaging probe. GB-6 has excellent in vivo stability, with tumor to pancreatic and intestinal fluorescence signal ratios of 5.2 and 6.3, respectively, in the SW1990 subcutaneous xenograft model. GB-6 can quickly target tumors, accurately depict tumor boundaries, and has broad application prospects.
Purity (HPLC) ≥98.0%
Single impurity≤2%
Peptide content≥75.0%
Amino Acid Composition≤±15%
Bacterial Endotoxins≤50EU/mg
Solubility：H2O/DMSO
Vacuum-packed with aluminum foil bag or transparent bag.Various weights can be packed according to your requirements.
Storage:Cool dry place( Store at -20°C, away from the light)
Remark:For Research Use Only. Not for human use.
Sequence(1-letter code) | Q-{Htp}-{β-Ala}-{Nva}-GH-NH2 |
Sequence(3-letter code) | H-Gln-{Htp}-{β-Ala}-{Nva}-Gly-His-NH2 |
Peptide Structure | 
|
Molecular Formula | C32H45N11O8 |
Molecular Weight | 711.77 |
訂購聯(lián)系方式：
南京肽研生物生物科技有限公司
手機號：19961912513(微信同號)
QQ: 2178255659
郵箱：sales@typeptide.com
聯(lián)系人：顧經(jīng)理
申明：本產(chǎn)品僅供科研使用，不得用于人體。
關鍵字： GB-6;靶向胃泌素釋放肽受體多肽;2413262-74-3;多肽;多肽合成;
肽研生物坐落于國家級新區(qū)南京江北新區(qū)新材料產(chǎn)業(yè)園，是一家專業(yè)從事多肽產(chǎn) 品的研發(fā)、生產(chǎn)和銷售以及多肽技術(shù)轉(zhuǎn)讓的高新技術(shù)企業(yè)。公司秉持“誠信、嚴 謹、務實”的匠人精神，持續(xù)投入研發(fā)，不斷創(chuàng)新，致力于為科研工作者提供豐 富全面的多肽修飾類型和優(yōu)質(zhì)的產(chǎn)品。