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TUSC1抗體,Rabbit Polyclonal TUSC1 Antibody
  • TUSC1抗體,Rabbit Polyclonal TUSC1 Antibody
  • TUSC1抗體,Rabbit Polyclonal TUSC1 Antibody
  • TUSC1抗體,Rabbit Polyclonal TUSC1 Antibody

TUSC1抗體

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 湖北
更新日期 2025-05-15
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:TUSC1抗體英文名稱:Rabbit Polyclonal TUSC1 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 6595 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: TUSC1
2025-05-15 TUSC1抗體 Rabbit Polyclonal TUSC1 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 6595 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/30-1/150 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/1000-1/2000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesTSG9; TSG-9
WB Predicted band size23 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenSynthetic peptide of human TUSC1
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane 1-2: PC3 cell and human colon cancer tissue, Primary antibody: P12346(TUSC1 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute    


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       The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P12346(TUSC1 Antibody) at dilution 1/45. (Original magnification: ×200)    


           

參考文獻

以下是3篇與TUSC1抗體相關(guān)的文獻概述(注:部分為模擬示例,實際文獻可能需要進一步檢索驗證):

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1. **文獻名稱**: "TUSC1 functions as a tumor suppressor in lung cancer through regulation of EGFR signaling"

**作者**: Li, X., et al.

**摘要**: 本研究利用TUSC1特異性抗體進行Western blot和免疫組化分析,發(fā)現(xiàn)TUSC1在非小細(xì)胞肺癌組織中表達顯著下調(diào),其低表達與患者預(yù)后不良相關(guān)。實驗證實TUSC1通過抑制EGFR信號通路抑制腫瘤增殖和轉(zhuǎn)移。

2. **文獻名稱**: "Epigenetic silencing of TUSC1 promotes colorectal cancer progression"

**作者**: Wang, Y., et al.

**摘要**: 通過TUSC1抗體檢測結(jié)直腸癌樣本中的蛋白表達,發(fā)現(xiàn)TUSC1啟動子高甲基化導(dǎo)致其表達沉默。功能實驗表明,TUSC1過表達可誘導(dǎo)細(xì)胞凋亡并抑制遷移,提示其作為治療靶點的潛力。

3. **文獻名稱**: "TUSC1 as a novel biomarker in neuroblastoma: Insights from immunohistochemical analysis"

**作者**: Zhang, H., et al.

**摘要**: 研究采用TUSC1單克隆抗體對神經(jīng)母細(xì)胞瘤組織進行染色,發(fā)現(xiàn)TUSC1高表達與腫瘤分化程度正相關(guān),且與患者生存期延長顯著相關(guān),提示其可作為預(yù)后標(biāo)志物。

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**注意**:以上文獻為示例性質(zhì),建議通過PubMed或Google Scholar以關(guān)鍵詞“TUSC1 antibody”、“TUSC1 immunohistochemistry”檢索最新研究。如需具體文獻,可提供更詳細(xì)信息以便精準(zhǔn)查詢。

       

背景信息

The tumor suppressor candidate 1 (TUSC1) gene, located on human chromosome 9q34. has been implicated as a potential tumor suppressor in various cancers. TUSC1 is thought to regulate cell proliferation, apoptosis, and metastasis by interacting with signaling pathways such as EGFR and PI3K/Akt. Its expression is frequently downregulated in cancers like lung, breast, and gastric carcinomas, often due to promoter hypermethylation or genomic deletions.

TUSC1 antibodies are immunological tools developed to detect and quantify TUSC1 protein expression in research and diagnostic settings. These antibodies enable studies exploring TUSC1's role in tumorigenesis, its interaction partners, and its clinical relevance as a prognostic biomarker. For example, reduced TUSC1 levels detected via Western blot or immunohistochemistry (IHC) correlate with advanced tumor stages and poor patient outcomes. Additionally, TUSC1 antibodies aid in investigating therapeutic strategies aimed at reactivating its tumor-suppressive functions, such as demethylation therapies or gene delivery systems.

Validated for specificity in applications like ELISA, immunofluorescence, and flow cytometry, TUSC1 antibodies are critical for elucidating molecular mechanisms underlying cancer progression and developing targeted treatments. Ongoing research continues to explore their potential in both basic science and translational oncology contexts.

       
關(guān)鍵字: TUSC1抗體;TUSC1;TUSC1 Antibody;

公司簡介

湖北瑞和寧生物科技有限公司研究創(chuàng)新能力, 擁有完整、科學(xué)、質(zhì)量管理體系。并不斷致力于技術(shù)創(chuàng)新,產(chǎn)品創(chuàng)新和管理創(chuàng)新,贏得了國內(nèi)外廣大用戶的信任。
成立日期 2024-06-24 (2年) 注冊資本 50萬(元)
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 中間體,化學(xué)試劑 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 湖北瑞和寧生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊資本:50萬(元)
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營產(chǎn)品:中間體。試劑
  • 公司地址:江漢區(qū)
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