同用名/別名(Synonym)
Interferon Alpha-2; IFN-Alpha-2; Interferon Alpha-A; LeIF A; IFNA2
描述(Description)
At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes only differ in their sequences by one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-terminal end.
純度(Purity)
≥95%, by SDS-PAGE (under reducing (R) & Non-reducing conditions, visualized by Coomassie staining)
生物活性(Bioactivity)
Measured in a VSV inhibition assay with Wish cells. The ED50 this effect is ≤100 pg/mL, corresponding to a specificBioactivity is ≥1 ×107 units/mg.
氨基酸序列(Target Protein Sequence)
CDLPQTHSLGSRRTLMLLAQMRRISLFSCLKDRHDFGFPQEEFGNQFQKAETIPVLHEMIQQIFNLFSTKDSSAAWDETLLDKFYTELYQQLNDLEACVIQGVGVTETPLMKEDSILAVRKYFQRITLYLKEKKYSPCAWEVVRAEIMRSFSLSTNLQESLRSKE
制劑(Trait)
Lyophilized after extensive dialysis against PBS pH 7.4 or 20 mM PB, 150 mM NaCl, pH 7.2.
復(fù)溶(Reconstitution)
It is recommended to redissolve in sterile deionized water.
保存條件&效期(Storage & Stability)
36 months at 2°C to 8°C in lyophilized state
6 months at -20°C to -80°C under sterile conditions after reconstitution
7-10 days at 2°C to 8° C under sterile conditions after reconstitution
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
運(yùn)輸方式(Shipping)
The product is shipped with blue ice

生物活性(Bioactivity)
Measured in a VSV inhibition assay with Wish cells. The ED50 this effect is ≤100 pg/mL, corresponding to a specificBioactivity is ≥1 ×107 units/mg.The Bioactivity of Y06301 was higher than the other competing product.

電泳(SDS-PAGE)
Recombinant Human IFN-α2b SDS-PAGE under reducing (R) & Non-reducing conditions. The gel was stained with Y06301 SDS-PAGE.
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關(guān)鍵字: GMP級(jí);高純度;批間一致;生物活性;科研專供;
在生物科技領(lǐng)域,豐度蛋白專注重組蛋白供應(yīng),以“豐度的風(fēng)帆為蛋白提供動(dòng)力,豐度為蛋白護(hù)航”為使命,賦能生命科學(xué)發(fā)展。
蘇州豐度依托先進(jìn)技術(shù)平臺(tái),打造成熟生產(chǎn)體系,嚴(yán)控基因工程設(shè)計(jì)、細(xì)胞培養(yǎng)、蛋白純化等環(huán)節(jié),優(yōu)化工藝與管理,確保產(chǎn)品高純度、高活性且批間一致。產(chǎn)品覆蓋基礎(chǔ)研究、生物醫(yī)藥研發(fā)等多領(lǐng)域,為科研及生產(chǎn)提供多樣、適配產(chǎn)品,助力突破技術(shù)難題 。