中文名稱:ADAMDEC1抗體 | 英文名稱:Rabbit Polyclonal ADAMDEC1 Antibody |
品牌: 艾普蒂 | 產(chǎn)地: 武漢 |
保存條件: Stored at -20°C for 3748 year. Avoid repeated freeze / thaw cycles. | 產(chǎn)品類別: 抗體 |
重組: 否 | 應用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA |
種屬反應性: Human,Mouse,Rat | 宿主: Rabbit |
偶聯(lián)物: 無 | 靶點: ADAMDEC1 |
WB | 咨詢技術(shù) | Human,Mouse,Rat |
IF | 咨詢技術(shù) | Human,Mouse,Rat |
IHC | 1/25-1/100 | Human,Mouse,Rat |
ICC | 技術(shù)咨詢 | Human,Mouse,Rat |
FCM | 咨詢技術(shù) | Human,Mouse,Rat |
Elisa | 1/2000-1/5000 | Human,Mouse,Rat |
Aliases | M12.219 |
Host/Isotype | Rabbit IgG |
Antibody Type | Primary antibody |
Storage | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Species Reactivity | Human |
Immunogen | Fusion protein of human ADAMDEC1 |
Formulation | Purified antibody in PBS with 0.05% sodium azide and 50% glycerol. |
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The image is immunohistochemistry of paraffin-embedded Human liver cancer tissue using P07781(ADAMDEC1 Antibody) at dilution 1/20. (Original magnification: ×200)
The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P07781(ADAMDEC1 Antibody) at dilution 1/20. (Original magnification: ×200)
以下是3-4條關(guān)于 **ADAMDEC1抗體** 的虛構(gòu)參考文獻示例(供參考,實際文獻需查閱數(shù)據(jù)庫):
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1. **文獻名稱**:*"Development of a Monoclonal Antibody Targeting ADAMDEC1 and Its Application in Colorectal Cancer Detection"*
**作者**:Smith A, et al. (2020)
**摘要**:本研究開發(fā)了一種針對ADAMDEC1胞外域的高特異性單克隆抗體,驗證了其在結(jié)直腸癌組織中的表達上調(diào),并證明其可用于免疫組化檢測,提示ADAMDEC1可能作為腫瘤進展的潛在標志物。
2. **文獻名稱**:*"ADAMDEC1 Expression in Immune Cells: Role in Inflammation and Antibody-Based Functional Analysis"*
**作者**:Johnson R, et al. (2018)
**摘要**:通過抗ADAMDEC1多克隆抗體,作者發(fā)現(xiàn)該蛋白在巨噬細胞和樹突狀細胞中特異性表達,并參與調(diào)控炎癥反應中的基質(zhì)降解,為自身免疫疾病治療提供新靶點。
3. **文獻名稱**:*"Proteolytic Activity of ADAMDEC1 in Rheumatoid Arthritis: Inhibition by Neutralizing Antibodies"*
**作者**:Lee H, et al. (2019)
**摘要**:利用ADAMDEC1中和抗體阻斷其蛋白水解活性,發(fā)現(xiàn)可顯著減少類風濕關(guān)節(jié)炎模型中的關(guān)節(jié)破壞,表明其作為治療性抗體的潛在價值。
4. **文獻名稱**:*"ADAMDEC1 as a Biomarker in Pancreatic Cancer: Validation via Immunohistochemistry and ELISA"*
**作者**:Brown K, et al. (2021)
**摘要**:通過商業(yè)化ADAMDEC1抗體進行組織微陣列分析,證實其在胰腺癌基質(zhì)中高表達,且血清ADAMDEC1水平與患者生存率負相關(guān)。
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**注**:以上內(nèi)容為模擬生成,實際文獻請通過PubMed、Web of Science等平臺檢索關(guān)鍵詞“ADAMDEC1 antibody”。
The ADAMDEC1 (A Disintegrin and Metalloproteinase Domain-Like Decysin 1) antibody targets a unique member of the ADAM family of proteases, which are involved in extracellular matrix remodeling, cell adhesion, and signaling. ADAMDEC1. also known as decysin-1. is distinct from other ADAM proteins due to its truncated structure, lacking a transmembrane domain and conserved cysteine-rich region, suggesting a specialized regulatory role. It is primarily expressed in immune cells, such as dendritic cells and macrophages, and is implicated in inflammatory processes, immune regulation, and cancer progression. Studies highlight its context-dependent functions: it may promote tumor growth in certain cancers (e.g., colorectal carcinoma) while acting as a tumor suppressor in others.
The ADAMDEC1 antibody is a critical tool for detecting and quantifying this protein in research. It enables the study of ADAMDEC1's expression patterns, localization, and interactions via techniques like Western blotting, immunohistochemistry, and flow cytometry. Its applications extend to exploring ADAMDEC1's role in diseases, including autoimmune disorders (e.g., rheumatoid arthritis) and infectious diseases. However, due to structural similarities within the ADAM family, antibody specificity must be rigorously validated using knockout controls or recombinant proteins. Commercial ADAMDEC1 antibodies are typically raised in rabbits or mice, with monoclonal and polyclonal variants available, tailored for different experimental needs.
成立日期 | 2024-06-24 (2年) | 注冊資本 | 50萬(元) |
員工人數(shù) | 1-10人 | 年營業(yè)額 | ¥ 100萬以內(nèi) |
主營行業(yè) | 中間體,化學試劑 | 經(jīng)營模式 | 貿(mào)易,工廠,試劑,定制,服務 |
產(chǎn)品名稱 | 價格 | 公司名稱 | 報價日期 | |
---|---|---|---|---|
¥1280 |
湖北艾普蒂生物工程有限公司
|
2025-06-04 | ||
¥1950 |
VIP3年
|
上海滬震實業(yè)有限公司
|
2025-08-01 | |
詢價 |
VIP3年
|
維百奧(北京)生物科技有限公司
|
2025-08-01 |