午夜插插,噜噜噜影院,啪啪伊人网,欧美熟夫,景甜吻戏视频,男人强操性感蕾丝美女视频在线网站,日本美女跳舞视频

IGF2BP2抗體,Rabbit Polyclonal IGF2BP2 Antibody
  • IGF2BP2抗體,Rabbit Polyclonal IGF2BP2 Antibody
  • IGF2BP2抗體,Rabbit Polyclonal IGF2BP2 Antibody
  • IGF2BP2抗體,Rabbit Polyclonal IGF2BP2 Antibody

IGF2BP2抗體

價格 詢價
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 湖北
更新日期 2025-05-11
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱:IGF2BP2抗體英文名稱:Rabbit Polyclonal IGF2BP2 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 1705 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 靶點: IGF2BP2
2025-05-11 IGF2BP2抗體 Rabbit Polyclonal IGF2BP2 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 1705 year. Avoid repeated freeze / thaw cycles. 抗體

驗證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/50-1/200 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/5000-1/10000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesIMP2; IMP-2; VICKZ2
WB Predicted band size66 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman, Mouse
ImmunogenFusion protein of human IGF2BP2
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

+ +

  •  

     

       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse heart tissue lysate, Primary antibody: P00445(IGF2BP2 Antibody) at dilution 1/1300, Secondary antibody: Goat anti rabbit IgG at 1/5000 dilution, Exposure time: 10 seconds    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human prostate cancer tissue using P00445(IGF2BP2 Antibody) at dilution 1/80. (Original magnification: ×200)    


  •  

     

       The image is immunohistochemistry of paraffin-embedded Human breast cancer tissue using P00445(IGF2BP2 Antibody) at dilution 1/80. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是3-4篇關(guān)于IGF2BP2抗體的參考文獻(xiàn)及其簡要摘要:

1. **"IGF2BP2 promotes colorectal cancer progression by recruiting MDH2 to enhance mTORC1 signaling"**

- **作者**: Huang et al.

- **摘要**: 研究利用IGF2BP2特異性抗體進(jìn)行免疫沉淀和Western blot分析,揭示了IGF2BP2通過調(diào)控MDH2-mTORC1軸促進(jìn)結(jié)直腸癌進(jìn)展的分子機(jī)制。

2. **"The RNA-binding protein IGF2BP2 sustains mitochondrial function in pancreatic cancer via m6A modification"**

- **作者**: Bell et al.

- **摘要**: 通過IGF2BP2抗體進(jìn)行免疫組化和RNA結(jié)合實驗,發(fā)現(xiàn)IGF2BP2通過m6A修飾維持線粒體功能,從而促進(jìn)胰腺癌細(xì)胞的存活和代謝適應(yīng)性。

3. **"IGF2BP2 enhances an aggressive phenotype in glioblastoma through stabilizing MYC mRNA"**

- **作者**: Janiszewska et al.

- **摘要**: 使用IGF2BP2抗體進(jìn)行免疫熒光和RNA穩(wěn)定性實驗,證實IGF2BP2通過穩(wěn)定MYC mRNA促進(jìn)膠質(zhì)母細(xì)胞瘤的侵襲性表型。

4. **"The role of IGF2BP2 in cancer: RNA-binding proteins as therapeutic targets"**

- **作者**: Krüger et al.

- **摘要**: 綜述性文獻(xiàn),總結(jié)了IGF2BP2在多種癌癥中的作用,并強(qiáng)調(diào)其抗體在診斷和靶向治療開發(fā)中的應(yīng)用潛力。

以上文獻(xiàn)均涉及IGF2BP2抗體在分子機(jī)制研究或臨床分析中的具體應(yīng)用。

       

背景信息

The insulin-like growth factor 2 mRNA-binding protein 2 (IGF2BP2), also known as IMP2. is a member of the conserved RNA-binding protein family that regulates mRNA stability, localization, and translation. It plays a critical role in post-transcriptional gene regulation, particularly in embryogenesis, metabolism, and cancer progression. IGF2BP2 binds to target mRNAs, including IGF2. MYC, and HMGA1. and enhances their expression by shielding them from degradation or promoting translational efficiency. Dysregulation of IGF2BP2 is linked to metabolic disorders like type 2 diabetes and various cancers, where it often acts as an oncoprotein by driving cell proliferation, invasion, and chemoresistance.

Antibodies against IGF2BP2 are essential tools for studying its expression, localization, and molecular interactions. They are widely used in techniques such as Western blotting, immunohistochemistry (IHC), immunofluorescence (IF), and RNA immunoprecipitation (RIP). Due to structural similarities among IGF2BP family members (IGF2BP1-3), high-specificity antibodies must be rigorously validated to avoid cross-reactivity. Commercial IGF2BP2 antibodies are typically raised against unique epitopes within its N-terminal RNA-binding domains or C-terminal regions. Researchers employ these antibodies to explore IGF2BP2's role in diseases, evaluate its prognostic value in cancer tissues, or investigate its interaction with RNA networks. Recent studies also highlight its potential as a therapeutic target, driving demand for reliable antibodies in preclinical research.

       
關(guān)鍵字: IGF2BP2抗體;IGF2BP2;IGF2BP2 Antibody;

公司簡介

湖北瑞和寧生物科技有限公司研究創(chuàng)新能力, 擁有完整、科學(xué)、質(zhì)量管理體系。并不斷致力于技術(shù)創(chuàng)新,產(chǎn)品創(chuàng)新和管理創(chuàng)新,贏得了國內(nèi)外廣大用戶的信任。
成立日期 2024-06-24 (2年) 注冊資本 50萬(元)
員工人數(shù) 1-10人 年營業(yè)額 ¥ 100萬以內(nèi)
主營行業(yè) 中間體,化學(xué)試劑 經(jīng)營模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 湖北瑞和寧生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊資本:50萬(元)
  • 企業(yè)類型:有限責(zé)任公司(自然人投資或控股)
  • 主營產(chǎn)品:中間體。試劑
  • 公司地址:江漢區(qū)
詢盤

店內(nèi)推薦

IGF2BP2抗體相關(guān)廠家報價

產(chǎn)品名稱 價格   公司名稱 報價日期
¥960.00
VIP10年
北京索萊寶科技有限公司
2025-07-30
詢價
VIP3年
維百奧(北京)生物科技有限公司
2025-08-01
¥1950
VIP3年
上海滬震實業(yè)有限公司
2025-08-01
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
內(nèi)容聲明:
以上所展示的信息由商家自行提供,內(nèi)容的真實性、準(zhǔn)確性和合法性由發(fā)布商家負(fù)責(zé)。 商家發(fā)布價格指該商品的參考價格,并非原價,該價格可能隨著市場變化,或是由于您購買數(shù)量不同或所選規(guī)格不同而發(fā)生變化。最終成交價格,請咨詢商家,以實際成交價格為準(zhǔn)。請意識到互聯(lián)網(wǎng)交易中的風(fēng)險是客觀存在的
主頁 | 企業(yè)會員服務(wù) | 廣告業(yè)務(wù) | 聯(lián)系我們 | 舊版入口 | 中文MSDS | CAS Index | 常用化學(xué)品CAS列表 | 化工產(chǎn)品目錄 | 新產(chǎn)品列表 |投訴中心
Copyright ? 2008 ChemicalBook 京ICP備07040585號  京公海網(wǎng)安備110108000080號  All rights reserved.