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FOXR2抗體,Rabbit Polyclonal FOXR2 Antibody
  • FOXR2抗體,Rabbit Polyclonal FOXR2 Antibody
  • FOXR2抗體,Rabbit Polyclonal FOXR2 Antibody
  • FOXR2抗體,Rabbit Polyclonal FOXR2 Antibody

FOXR2抗體

價(jià)格 詢價(jià)
包裝 20μl 50μl 100μl
最小起訂量 1μl
發(fā)貨地 湖北
更新日期 2025-05-11
QQ交談 微信洽談

產(chǎn)品詳情

中文名稱(chēng):FOXR2抗體英文名稱(chēng):Rabbit Polyclonal FOXR2 Antibody
品牌: 艾普蒂產(chǎn)地: 武漢
保存條件: Stored at -20°C for 1681 year. Avoid repeated freeze / thaw cycles.產(chǎn)品類(lèi)別: 抗體
重組: 應(yīng)用: WB: IHC-P:?IHC-F:?ICC/IF: IP:FC:ChIP:?ELISA
種屬反應(yīng)性: Human,Mouse,Rat 宿主: Rabbit
偶聯(lián)物: 無(wú)靶點(diǎn): FOXR2
2025-05-11 FOXR2抗體 Rabbit Polyclonal FOXR2 Antibody 20μl/RMB;50μl/RMB;100μl/RMB 艾普蒂 武漢 Stored at -20°C for 1681 year. Avoid repeated freeze / thaw cycles. 抗體

驗(yàn)證與應(yīng)用

應(yīng)用及物種
WB咨詢技術(shù) Human,Mouse,Rat
IF咨詢技術(shù) Human,Mouse,Rat
IHC1/25-1/100 Human,Mouse,Rat
ICC技術(shù)咨詢 Human,Mouse,Rat
FCM咨詢技術(shù) Human,Mouse,Rat
Elisa1/1000-1/2000 Human,Mouse,Rat
   

產(chǎn)品詳情

AliasesFOXN6
WB Predicted band size36 kDa
Host/IsotypeRabbit IgG
Antibody TypePrimary antibody
StorageStore at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Species ReactivityHuman
ImmunogenFull length fusion protein
FormulationPurified antibody in PBS with 0.05% sodium azide and 50% glycerol.

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       Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Raji cell, Primary antibody: P00376(FOXR2 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 2 minutes    


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       The image is immunohistochemistry of paraffin-embedded Human lung cancer tissue using P00376(FOXR2 Antibody) at dilution 1/25. (Original magnification: ×200)    


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       The image is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using P00376(FOXR2 Antibody) at dilution 1/25. (Original magnification: ×200)    


           

參考文獻(xiàn)

以下是關(guān)于FOXR2抗體的參考文獻(xiàn)示例(注:以下內(nèi)容為模擬示例,實(shí)際文獻(xiàn)需通過(guò)學(xué)術(shù)數(shù)據(jù)庫(kù)查詢):

1. **"FOXR2 as a novel oncogene in neuroblastoma: Characterization of a polyclonal antibody for clinical analysis"**

*Authors: Smith A, et al. (2021)*

摘要:本研究開(kāi)發(fā)了一種兔源多克隆FOXR2抗體,驗(yàn)證了其在免疫組化和Western blot中的特異性,并發(fā)現(xiàn)FOXR2高表達(dá)與神經(jīng)母細(xì)胞瘤患者不良預(yù)后相關(guān)。

2. **"FOXR2 regulates neural crest cell migration via antibody-based profiling in avian models"**

*Authors: Chen L, et al. (2019)*

摘要:通過(guò)制備FOXR2單克隆抗體,研究揭示了FOXR2在神經(jīng)嵴細(xì)胞遷移中的動(dòng)態(tài)表達(dá)模式,為胚胎發(fā)育機(jī)制提供了新見(jiàn)解。

3. **"A monoclonal antibody targeting FOXR2 inhibits glioma cell invasion in vitro"**

*Authors: Wang X, et al. (2020)*

摘要:報(bào)道了一種人源化FOXR2單克隆抗體的開(kāi)發(fā),體外實(shí)驗(yàn)表明其可通過(guò)阻斷FOXR2與下游信號(hào)分子相互作用抑制膠質(zhì)瘤細(xì)胞侵襲。

4. **"CRISPR/Cas9 validation and subcellular localization of FOXR2 using a custom antibody in hepatocellular carcinoma"**

*Authors: Kim H, et al. (2022)*

摘要:結(jié)合CRISPR/Cas9基因編輯技術(shù),利用自研FOXR2抗體證實(shí)了其在肝癌細(xì)胞核中的定位,并探討了其轉(zhuǎn)錄調(diào)控功能。

建議通過(guò)PubMed或Google Scholar檢索最新文獻(xiàn),結(jié)合關(guān)鍵詞“FOXR2 antibody”及研究領(lǐng)域(如癌癥、發(fā)育生物學(xué))獲取準(zhǔn)確信息。

       

背景信息

The FOXR2 antibody is a research tool designed to target the FOXR2 protein, a member of the Forkhead box (FOX) family of transcription factors. FOX proteins play critical roles in regulating gene expression during development, differentiation, and disease. FOXR2. specifically, is a relatively understudied member of this family. It shares a conserved Forkhead DNA-binding domain but exhibits distinct expression patterns and functions compared to other FOX proteins. Emerging studies suggest FOXR2 may be involved in oncogenesis, with elevated expression observed in certain cancers, including neuroblastoma and glioblastoma. Its exact mechanisms, however, remain unclear, though it is hypothesized to influence cell proliferation, survival, or metabolic reprogramming.

FOXR2 antibodies are primarily used in biomedical research to detect and quantify FOXR2 protein levels in tissues or cell lines, aiding in studies of its biological roles and pathological relevance. These antibodies are validated for techniques like Western blotting, immunohistochemistry, and immunofluorescence. Commercially available FOXR2 antibodies are typically monoclonal or polyclonal, with specificity confirmed via knockout controls.

Interest in FOXR2 has grown due to its potential as a diagnostic marker or therapeutic target, particularly in cancers with limited treatment options. However, further research is needed to elucidate its signaling pathways and interactions. Current challenges include optimizing antibody specificity and understanding FOXR2's context-dependent roles in different tissues or malignancies.

       
關(guān)鍵字: FOXR2抗體;FOXR2;FOXR2 Antibody;

公司簡(jiǎn)介

湖北瑞和寧生物科技有限公司研究創(chuàng)新能力, 擁有完整、科學(xué)、質(zhì)量管理體系。并不斷致力于技術(shù)創(chuàng)新,產(chǎn)品創(chuàng)新和管理創(chuàng)新,贏得了國(guó)內(nèi)外廣大用戶的信任。
成立日期 2024-06-24 (2年) 注冊(cè)資本 50萬(wàn)(元)
員工人數(shù) 1-10人 年?duì)I業(yè)額 ¥ 100萬(wàn)以內(nèi)
主營(yíng)行業(yè) 中間體,化學(xué)試劑 經(jīng)營(yíng)模式 貿(mào)易,工廠,試劑,定制,服務(wù)
  • 湖北瑞和寧生物科技有限公司
VIP 1年
  • 公司成立:2年
  • 注冊(cè)資本:50萬(wàn)(元)
  • 企業(yè)類(lèi)型:有限責(zé)任公司(自然人投資或控股)
  • 主營(yíng)產(chǎn)品:中間體。試劑
  • 公司地址:江漢區(qū)
詢盤(pán)

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FOXR2抗體相關(guān)廠家報(bào)價(jià)

產(chǎn)品名稱(chēng) 價(jià)格   公司名稱(chēng) 報(bào)價(jià)日期
¥1280
湖北艾普蒂生物工程有限公司
2025-06-04
¥960.00
VIP10年
北京索萊寶科技有限公司
2025-07-30
詢價(jià)
VIP3年
維百奧(北京)生物科技有限公司
2025-08-01
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