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Postion:Product Catalog >ZT-12-037-01
ZT-12-037-01
  • ZT-12-037-01

ZT-12-037-01 NEW

Price $30 $68 $117
Package 1mg 5mg 10mg
Min. Order:
Supply Ability: 10g
Update Time: 2025-07-27

Product Details

Product Name: ZT-12-037-01 CAS No.: 2328073-61-4
Purity: 99.56% Supply Ability: 10g
Release date: 2025/07/27

Product Introduction

Bioactivity

NameZT-12-037-01
DescriptionZt-12-037-01 is a ATP competitive STK19 inhibitor(IC50 values of 23.96 nM and 27.94 nM for STK19 (WT) and STK19 (D89N),respectively).
Animal ResearchZT-12-037-01 (injection subcutaneously; 25-50 mg/kg; once daily; 21 days) inhibits growth of SK-MEL-2 xenograft melanoma and the sections of tumors indicates induction of apoptosis by increasing cleaved caspase-3.
In vitroZT-12-037-01 significantly inhibits mutant NRAS-STK19-driven melanocyte colony formation and proliferation.
In vivoZT-12-037-01 as a specific STK19-targeted inhibitor and it effectively blocks oncogenic NRAS-driven melanocyte malignant transformation and melanoma growth in vivo.
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility InformationDMSO : 41 mg/mL (106.36 mM), Sonication is recommended.
KeywordsZT-12-037-01 | ZT1203701 | ZT 12 037 01 | STK19 | SerineProtease | Serine Protease | Ras | Inhibitor | inhibit
Inhibitors RelatedNafamostat mesylate | PMSF | AEBSF hydrochloride | Ketoconazole | Salirasib | RMC-6236 | (S)-(-)-Perillyl alcohol | Ceritinib | Aprotinin | CASIN | 4-Aminobenzamidine dihydrochloride | Benzamidine hydrochloride
Related Compound LibrariesHighly Selective Inhibitor Library | Ferroptosis Compound Library | Bioactive Compound Library | Pain-Related Compound Library | Membrane Protein-targeted Compound Library | Kinase Inhibitor Library | Glutamine Metabolism Compound Library | Inhibitor Library | Stem Cell Differentiation Compound Library | Immunology/Inflammation Compound Library | Bioactive Compounds Library Max | GPCR Compound Library

Company Profile Introduction

Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers. TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.

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