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Postion:Product Catalog >Phorbol-12
Phorbol-12
  • Phorbol-12

Phorbol-12 NEW

Price $5 $4 $2
Package 1kg 10kg 100kg
Min. Order: 1kg
Supply Ability: 100kg
Update Time: 2025-07-08

Product Details

Product Name: Phorbol-12 CAS No.: 37558-16-0
Min. Order: 1kg Purity: 99%
Supply Ability: 100kg Release date: 2025/07/08
Lead time: in stock Packaging: bag/bottle/drum//IBC, as request
Delivery: By sea, by air, by express Origin: Manufacturer, advantage products
COA, MSDS: Available, contact us for details Contact: Tina

PRODUCT INFORMATION

Names

Namephorbol 12,13-dibutanoate
SynonymMore Synonyms

 Phorbol-12 Biological Activity

DescriptionPhorbol 12,13-dibutyrate (Phorbol dibutyrate) is a PKC activator and a potent skin tumor promoter[1][2].
Related Catalog
Signaling Pathways >> Epigenetics >> PKC
Research Areas >> Cancer
Signaling Pathways >> TGF-beta/Smad >> PKC
Target

PKC[1]

In VitroPhorbol 12,13-dibutyrate (Phorbol dibutyrate) (1 MM) activates PKC and inhibited Na/K-ATPase transport activity in OK cells[3].
References

[1]. Singh J, et al. Immunocytochemical evidence for PDBu-induced activation of RhoA/ROCK in human internal anal sphincter smooth muscle cells. Am J Physiol Gastrointest Liver Physiol. 2011 Aug;301(2):G317-25.

[2]. Szallasi Z, et al. Dissociation of phorbol esters leads to immediate redistribution to the cytosol of protein kinases C alpha and C delta in mouse keratinocytes. J Biol Chem. 1994 Nov 4;269(44):27159-62.

[3]. Middleton JP, et al. Heterogeneity of protein kinase C-mediated rapid regulation of Na/K-ATPase in kidney epithelial cells. J Biol Chem. 1993 Jul 25;268(21):15958-64.

 Chemical & Physical Properties

Density1.27g/cm3
Boiling Point623.4oC at 760mmHg
Molecular FormulaC28H40O8
Molecular Weight504.61200
Flash Point199.3oC
Exact Mass504.27200
PSA130.36000
LogP2.63210
Appearance of Characterspowder | clear, light yellow, film
Index of Refraction1.574
Storage condition?20°C
Water SolubilityH2O: 30 μM

 Safety Information

Personal Protective Equipmentdust mask type N95 (US);Eyeshields;Gloves
Hazard CodesXi: Irritant;
Risk Phrases36/37/38
Safety PhrasesS26-S36
RIDADR2928
WGK Germany3
RTECSEK7767000
Packaging GroupII
Hazard Class6.1(a)



Company Profile


Our company is a high-tech enterprise specializing in chemical raw materials such as electronic materials, optoelectronic materials, semiconductor materials, UV monomers, silane catalysts, cosmetic raw materials, etc. The company integrates research and development, production, customized synthesis, and sales, and is committed to providing customers with high-quality chemical product solutions.



Our Company

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Our Advantage

Rich experience

Our products have been exported to many countries, including Germany, Spain, the United Kingdom, the United States, Australia, the Middle East, Asia, and more. We have received highly positive feedback from our clients and have established long-term friendly cooperative relationships with them.

Excellent quality, purity, and competitive price

Excellent quality is one of the cornerstones of our success. We welcome ordering samples for quality testing.

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Safe and fast delivery

We will arrange shipment of spot products as soon as we receive payment.

Customized products are determined based on the synthesis time of different products.

 

Excellent pre-sales and after-sales service

Pre sales:

We are committed to providing the most favorable quotes and detailed information about our products and company.

after-sale service:

We assist buyers in customs clearance by providing necessary documents and information.

If there is any dispute over product quality, we are committed to providing the best solution.

 

? Packaging: 

1kg/bag, 25kg/drum, 50kg/drum, 180kg/drum, 200kg/drum, 1T/bag/drum, standard export packaging or packaging required by customers


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Shipping

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? Delivery:

Within 7 days after receiving your payment


Contact information

For more details, pls contact us freely.

Contact name: Tina

Email address: Tina@fdachem.com

Mob: 86 13213167925

WhatsApp/Skype/Wechat/LINE: 86 15225627621




Company Profile Introduction

Our company is a high-tech enterprise specializing in chemical raw materials such as electronic materials, optoelectronic materials, semiconductor materials, UV monomers, silane catalysts, cosmetic raw materials, etc. The company integrates research and development, production, customized synthesis, and sales, and is committed to providing customers with high-quality chemical product solutions. With our agile custom synthesis capabilities and responsive supply chain system, our products have gained widespread adoption across Asian markets including Japan, South Korea, Singapore, and Malaysia, while also expanding deeply into Europe and the Americas. We have forged long-term strategic partnerships with numerous leading global enterprises in the sector. "Driving value through technology and earning trust through service" is our core mission. Looking ahead, we will continue to focus on technological breakthroughs and green innovation in new materials, collaborating with partners to build a high-quality industrial ecosystem and provide globally competitive solutions with greater foresight.

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