
Vismodegib Impurity 3 NEW
Price | Get Latest Price | ||
Package | 10mg | 50mg | 100mg |
Min. Order: | 10mg |
Supply Ability: | 1000 |
Update Time: | 2025-07-31 |
Product Details
Product Name: Vismodegib Impurity 3 | CAS No.: 1370525-63-5 |
Min. Order: 10mg | Purity: 99%+ HPLC |
Supply Ability: 1000 | Release date: 2025/07/31 |
Molecular formula: C19H14Cl2N2O4S |
Vismodegib Impurity 3;1370525-63-5
WhatsAPP: +86 17386083646
E-mail: anna@molcoo.com.
Product Information
Product Number: V043003
English Name: Vismodegib Impurity 3
English Alias: 2-chloro-N-(4-chloro-3-hydroxy-5-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide
CAS Number: 1370525-63-5
Molecular Formula: C??H??Cl?N?O?S
Molecular Weight: 437.30
Advantages
Well-defined and distinct structure: The unique structure with a hydroxyl group introduced at the 3-position of the benzene ring is clearly different from the parent Vismodegib, containing functional groups such as chlorine atoms, hydroxyl groups, methylsulfonyl groups, and pyridine rings. It can be accurately identified by techniques like HPLC and LC-MS, providing a specific marker for impurity detection;
High stability and traceability: The hydroxyl structure is stable under conventional storage conditions and directly related to the hydroxylation metabolic pathway of Vismodegib. It can specifically reflect the degradation trend of the drug under oxidation or enzyme catalysis, improving the accuracy of impurity source analysis;
Outstanding value as a detection standard: As a key impurity in the synthesis or metabolism of Vismodegib, its structural characteristics provide a standard for establishing exclusive detection methods, enabling effective differentiation between the parent drug and other hydroxylated by-products and improving quantitative precision.
Applications
Pharmaceutical quality control: Used as an impurity reference standard to identify and quantify Impurity 3 in Vismodegib APIs and formulations, ensuring product purity meets pharmacopoeia and regulatory requirements;
Stability studies: Monitoring the generation of this impurity under light, high temperature, and oxidation conditions to evaluate the storage stability of Vismodegib formulations and support the development of appropriate packaging and storage conditions;
Metabolic mechanism research: As a potential product of Vismodegib's in vivo hydroxylation metabolism, it is used to explore the drug's metabolic pathway in the liver and analyze the impact of hydroxylation on drug activity and toxicity.
Product Information
Product Number: V043003
English Name: Vismodegib Impurity 3
English Alias: 2-chloro-N-(4-chloro-3-hydroxy-5-(pyridin-2-yl)phenyl)-4-(methylsulfonyl)benzamide
CAS Number: 1370525-63-5
Molecular Formula: C??H??Cl?N?O?S
Molecular Weight: 437.30
Advantages
Well-defined and distinct structure: The unique structure with a hydroxyl group introduced at the 3-position of the benzene ring is clearly different from the parent Vismodegib, containing functional groups such as chlorine atoms, hydroxyl groups, methylsulfonyl groups, and pyridine rings. It can be accurately identified by techniques like HPLC and LC-MS, providing a specific marker for impurity detection;
High stability and traceability: The hydroxyl structure is stable under conventional storage conditions and directly related to the hydroxylation metabolic pathway of Vismodegib. It can specifically reflect the degradation trend of the drug under oxidation or enzyme catalysis, improving the accuracy of impurity source analysis;
Outstanding value as a detection standard: As a key impurity in the synthesis or metabolism of Vismodegib, its structural characteristics provide a standard for establishing exclusive detection methods, enabling effective differentiation between the parent drug and other hydroxylated by-products and improving quantitative precision.
Applications
Pharmaceutical quality control: Used as an impurity reference standard to identify and quantify Impurity 3 in Vismodegib APIs and formulations, ensuring product purity meets pharmacopoeia and regulatory requirements;
Stability studies: Monitoring the generation of this impurity under light, high temperature, and oxidation conditions to evaluate the storage stability of Vismodegib formulations and support the development of appropriate packaging and storage conditions;
Metabolic mechanism research: As a potential product of Vismodegib's in vivo hydroxylation metabolism, it is used to explore the drug's metabolic pathway in the liver and analyze the impact of hydroxylation on drug activity and toxicity.
This product is intended for laboratory use only!
WhatsAPP: +86 17386083646
E-mail: anna@molcoo.com
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