Product Details
| Product Name:
Spathulenol |
CAS No.:
6750-60-3 |
| Purity:
99.20% |
Supply Ability:
10g |
| Release date:
2025/06/22 |
Product Introduction
Bioactivity
| Name | Spathulenol |
| Description | Spathulenol is a natural ingredient from Aristolochia yunnanensis that has anti-inflammatory, antioxidant, anti-proliferation, anti-ulcer and anti-mycobacterium activities. Spathulenol showed significant antioxidant activity in DPPH system with IC50 of 85.60 μg/mL. |
| In vitro | In the DPPH and MDA systems, spathulenol demonstrates high antioxidant activity. It shows significant DPPH free radical activity, with IC50 values of 85.60 μg/mL[1]. |
| In vivo | Spathulenol, when administered orally at a dose of 300 mg/kg, demonstrates significant inhibition in the mice paw edema and pleurisy model induced by Cg[1].
In a spontaneous lipoperoxidation model using rat brain homogenate, when incubated under controlled temperature and oxygenation conditions, PG-1 exhibits high activity with an IC50 value of 26.13 μg/mL. This activity is comparable to that of the commercial antioxidant BHT (38.41 μg/mL). Consequently, PG-1 contributes to a reduction in the generation of malondialdehyde (MDA), a toxic product resulting from the degradation of cell membranes through lipid peroxidation. This reduction in MDA levels helps prevent cell ruptures and mutations[1]. |
| Storage | store at low temperature,keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice./Shipping at ambient temperature. |
| Solubility Information | DMSO : 90 mg/mL (408.44 mM), Sonication is recommended.
|
| Keywords | Spathulenol | P-gp | Fungal | Caspase | Antioxidant |
| Inhibitors Related | Dehydroacetic acid sodium | Potassium gluconate | 5-Hydroxymethylfurfural | Methyl 2-amino-5-bromobenzoate | Terbinafine hydrochloride | AFMK | Lauryl betaine | Geraniol | Luliconazole | L-Cystine | L-Citronellol | 6-PPD |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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Recommended supplier
| Product name |
Price |
|
Suppliers |
Update time |
|
|
$8.00/1KG |
VIP6Y
|
Career Henan Chemical Co
|
2020-02-20 |
United States