NSC 80467 NEW
| Price | $113 |
| Package | 2mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-27 |
Product Details
| Product Name: NSC 80467 | CAS No.: 101982-51-8 |
| Supply Ability: 10g | Release date: 2025/07/27 |
Product Introduction
Bioactivity
| Name | NSC 80467 |
| Description | NSC 80467, a selective DNA damaging agent, functions by inhibiting survivin. Specifically, it preferentially targets DNA synthesis, leading to the induction of two distinct markers of DNA damage, namely γH2AX and pKAP1. |
| In vitro | NSC 80467 exhibits an activity profile against the NCI-60 cell line panel similar to its suppression of survivin expression and correlates with DNA-damaging agents through COMPARE analysis. It preferentially targets DNA synthesis and triggers a DNA damage response, marked by increased levels of γH2AX and pKAP1, at doses lower than those required to suppress survivin expression. At concentrations of 200 or 800 nM over 24 hours, NSC 80467 effectively inhibits survivin expression in PC3 cells, as demonstrated by Western Blot Analysis[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | NSC 80467 | NSC-80467 | NSC80467 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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