
NSC-70220 NEW
Price | $242 | $297 | $987 |
Package | 2mg | 5mg | 25mg |
Min. Order: | |
Supply Ability: | 10g |
Update Time: | 2025-07-17 |
Product Details
Product Name: NSC-70220 | CAS No.: 4551-00-2 |
Supply Ability: 10g | Release date: 2025/07/17 |
Product Introduction
Bioactivity
Name | NSC-70220 |
Description | SOS1-IN-1 is an inhibitor of SOS1. |
In vitro | SOS1-IN-1 (40 μM) and NSC-658497(30 μM) result in growth inhibitory rate of 29% and 8% respectively. The combination treatment results in growth inhibitory rate of 54%, showing the synergistic effect of SOS1-IN-1 and NSC-658497 on cell growth inhibition. It is showed that the treatment with NSC-658497 at 40 μM for 2 hours alone or in combìnation with the treatment with 40 μM of SOS1-IN-1 overnight resulted in lower expression levels of P-AKT and P-ERK. The treatment wlth 40 μM of SOS1-IN-1 overnight resulted in lower expression levels of P-ERK. |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
Solubility Information | DMSO : 12.5 mg/mL (38.42 mM), Sonication is recommended. |
Keywords | SOS1 | NSC-70220 | NSC70220 | NSC 70220 |
Inhibitors Related | Regorafenib monohydrate | Exarafenib | Doramapimod | Vemurafenib | Sulindac sulfide | Sorafenib | Regorafenib | Dabrafenib | Sorafenib tosylate | PLX-4720 | LY3009120 | GW 441756 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
You may like
Recommended supplier
Product name | Price | Suppliers | Update time | |
---|---|---|---|---|
$0.00/1g |
VIP1Y
|
Wuhan Circle Star Chem-medical Technology Co.,Ltd
|
2025-01-10 | |
$50.00/1kg |
VIP1Y
|
Hebei Zhuanglai Chemical Trading Co Ltd
|
2024-11-29 | |
$98.00/1mg |
VIP5Y
|
TargetMol Chemicals Inc.
|
2025-06-17 |
- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
INQUIRY