Lipid 5 NEW
| Price | $954 | $1570 |
| Package | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-06-16 |
Product Details
| Product Name: Lipid 5 | CAS No.: 2089251-33-0 |
| Supply Ability: 10g | Release date: 2025/06/16 |
Product Introduction
Bioactivity
| Name | Lipid 5 |
| Description | Lipid 5, an amino lipid compound, demonstrates proficient mRNA delivery in rodent and primate models, with favorable pharmacokinetics and minimal toxicity. |
| In vitro | Substituting the linoleic tail for a primary ester-containing lipid tail (Lipid 5) enhances expression and optimizes tissue clearance. Metabolite identification studies on Lipid 5 revealed that the initial metabolic step involves the hydrolysis of the primary ester[1]. |
| In vivo | The clearance of Lipid 5 and MC3 from various mouse tissues was evaluated following the administration of 0.05 mg/kg mRNA on days 1, 8, and 15 in CD-1 female mice. The liver and spleen exhibited the highest concentrations of Lipid 5, albeit at significantly lower levels than those of MC3. Detection of Lipid 5 also occurred in the plasma, lung, and kidney, but not in the heart[1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year |
| Keywords | Lipid 5 |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, USA
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