JC-10 NEW
| Price | $569 |
| Package | 1mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-07-22 |
Product Details
| Product Name: JC-10 | CAS No.: 5563-28-0 |
| Purity: 95% | Supply Ability: 10g |
| Release date: 2025/07/22 |
Product Introduction
Bioactivity
| Name | JC-10 |
| Description | JC-10 is a potent inhibitor of metalloproteinases and is often used as a probe. |
| Cell Research | Instructions 1. Solution preparation 1. Stock solution preparation: Dissolve JC-10 dye in anhydrous DMSO to prepare a 100× stock solution. 2. Working solution preparation: Dilute the stock solution to the working concentration using preheated cell culture medium. For example, add 10 μL of JC-10 stock solution to 1 mL of preheated culture medium and mix until the solution changes from pink to nearly colorless. 2. Operation steps Cell staining 1. Add the dye working solution to the cells, ensuring that the cells are completely immersed. 2. Incubate at 37°C in the dark for 15-30 minutes. 3. Washing: After incubation, remove the dye working solution. 4. Wash the cells 2-3 times with preheated PBS or culture medium to remove unbound dye. 5. Detection: Detect using a fluorescence microscope or flow cytometer. JC-10 forms aggregates in the mitochondria of healthy cells, showing orange-red fluorescence (excitation/emission wavelength: 540/590 nm); when the membrane potential decreases, JC-10 exists in monomeric form, showing green fluorescence (excitation/emission wavelength: 490/525 nm). Notes: 1) Wear gloves during operation to avoid contact between skin or mucous membranes and reagents. 2) Avoid light during incubation and storage to prevent fluorescence quenching. 3) After staining, fluorescence detection analysis should be performed as soon as possible. |
| Storage | keep away from direct sunlight,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Keywords | MMP | JC-10 | JC10 | JC 10 |
| Inhibitors Related | Stigmasterol | Doxycycline (hyclate) | Chondroitin sulfate | Tetrahexyldecyl ascorbate | Astragaloside IV | Doxycycline | Edaravone | Glucosamine | Bovine Type II Collagen | Triolein | Methylchloroisothiazolinone/Methylisothiazolinone Mixture | Glucosamine sulfate |
Company Profile Introduction
Target Molecule Corp. (TargetMol) is a global high-tech enterprise, headquartered in Boston, MA, specializing in chemical and biological research product and service to meet the research needs of global customers.
TargetMol has evolved into one of the biggest global compound library and small molecule suppliers and a customer based on 40+ countries. TargetMol offers over 80 types of compound libraries and a wide range of high-quality research chemicals including inhibitors, activator, natural compounds, peptides, inhibitory antibodies, and novel life-science kits, for laboratory and scientific use. Besides, virtual screening service is also available for customers who would like to conduct the computer-aided drug discovery.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, MA
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