Anti-infective agent 5 NEW
| Price | $1520 | $1980 | $2500 |
| Package | 25mg | 50mg | 100mg |
| Min. Order: | |
| Supply Ability: | 10g |
| Update Time: | 2025-05-02 |
Product Details
| Product Name: Anti-infective agent 5 | CAS No.: 2738381-47-8 |
| Supply Ability: 10g | Release date: 2025/05/02 |
Product Introduction
Bioactivity
| Name | Anti-infective agent 5 |
| Description | Anti-infective agent 5 (compound 74) is an orally active inhibitor of Trypanosoma cruzi with an IC50 value of 0.10 μM, demonstrating efficacy in reducing parasite burden in vivo and holding promising potential for infection research. [1] |
| In vitro | The anti-infective agent 5, administered at concentrations ranging from 0.1 nM to 100 μM for 48 hours, exhibits antitrypanosomal effects against T. cruzi amastigotes within 3T3 cells, achieving an IC50 of 0.10 μM [1]. Furthermore, in cytotoxicity assays conducted on the 3T3 cell line under the same conditions, the compound demonstrated a CC50 value of over 37 μM, indicating its activity and potential selectivity towards the pathogen while maintaining a lower toxicity profile towards the host cells [1]. |
| In vivo | The anti-infective agent 5, administered orally at a dosage of 50 mg/kg twice daily for five days, significantly reduced the parasite burden in a BALB/c mouse model infected with bioluminescent T. cruzi CL Brener parasites. This treatment resulted in a greater than 98-99% decrease in parasite levels without causing notable adverse effects in the mice [1]. |
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Company Profile Introduction
TargetMol Chemicals Inc. is headquartered in Boston, MA, and specializes in products and services that serve the research needs of chemical and biological scientists worldwide. With a client base in 40+ countries, TargetMol has evolved into one of the biggest global research suppliers for compound libraries and small molecule compounds.
170+ Compound Libraries， 10000+ Noval Small Molecucles，16000+ Nature Compounds
TargetMol diligently updates and offers over 170 types of compound libraries and a wide range of high-quality research chemicals, including inhibitors, activators, natural products, peptides, antibodies , and novel life-science kits for laboratory and scientific use. In addition, our lab allows us to conduct CADD (computer-aided drug design) and chemical synthesis to meet the customization needs of our clients.
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United States- Since: 2011-01-07
- Address: 36 Washington Street, Wellesley Hill, Massachusetts, USA
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