| Company Name: |
Artis Biotech Co. Ltd.
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| Tel: |
028-67271278 18582380095 |
| Email: |
sales@artisbio.com |
| Products Intro: |
Product Name:Sofosbuvir 13CD3
Purity:99% HPLC Package:5mg 20mg 50mg 100mg 200mg 1g
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| Company Name: |
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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| Tel: |
18818260767 |
| Email: |
sales@chemegen.com |
| Products Intro: |
Product Name:PSI-7977-13C-d3
CAS:2070009-25-3
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g
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| | PSI-7977-13C-d3 Basic information |
| Product Name: | PSI-7977-13C-d3 | | Synonyms: | [13C,2H3]-Sofosbuvir;isopropyl((S)-(((2R,3R,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-4-fluoro-3-hydroxy-4-(methyl-13C-d3)tetrahydrofuran-2-yl)methoxy)(phenoxy)phosphoryl)-L-alaninate;Sofosbuvir 13CD3Q: What is
Sofosbuvir 13CD3 Q: What is the CAS Number of
Sofosbuvir 13CD3 Q: What is the storage condition of
Sofosbuvir 13CD3 Q: What are the applications of
Sofosbuvir 13CD3;PSI-7977-13C-d3;L-Alanine, N-[[P(S),2′R]-2′-deoxy-2′-fluoro-2′-(methyl-13C-d3)-P-phenyl-5′-uridylyl]-, 1-methylethyl ester | | CAS: | 2070009-25-3 | | MF: | C22H26D3FN3O9P | | MW: | 533.46 | | EINECS: | | | Product Categories: | | | Mol File: | 2070009-25-3.mol |  |
| | PSI-7977-13C-d3 Chemical Properties |
| density | 1.413±0.10 g/cm3(Temp: 25 °C; Press: 760 Torr)(predicted) | | storage temp. | Store at -20°C | | solubility | DMF: 20 mg/ml,DMSO: 20 mg/ml,Ethanol: 25 mg/ml,PBS (pH 7.2): 0.2 mg/ml | | form | A solid |
| | PSI-7977-13C-d3 Usage And Synthesis |
| Description | PSI-7977-13C-d3 is intended for use as an internal standard for the quantification of PSI-7977 by GC- or LC-MS. PSI-7977 is a phosphoramidate prodrug of PSI-7851, a nucleoside analog that, when phosphorylated, inhibits the RNA-dependent RNA polymerase of hepatitis C virus (EC50 = 92 nM). PSI-7977 is effective in vitro and in vivo. | | Uses | PSI-7977-13CD3 is the isotope labelled analog of PSI-7977. PSI-7977 is a prodrug that is metabolized to the active antiviral agent 2''-deoxy-2''-α-fluoro-β-C-methyluridine-5''-monophosphate and is currently being investigated in phase 3 clinical trials for the treatment of hepatitis C. Studies have profiled PSI-7977 as a nucleotide inhibitor of hepatitis C virus, exerting selective inhibitory effects towards HCV NS5B polymerase. |
| | PSI-7977-13C-d3 Preparation Products And Raw materials |
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