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| | 2-Hydroxymethyl Loratadine Basic information |
| Product Name: | 2-Hydroxymethyl Loratadine | | Synonyms: | 4-[8-Chloro-5,6-dihydro-2-(hydroxymethyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-1-piperidinecarboxylic Acid Ethyl Ester;Loratadine 2-Hydroxymethyl Impurity (USP);2-Hydroxymethyl Loratadine;4-[8-Chloro-5,6-dihydro-2-(hydroxymethyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-1-piperidinecarboxylic Acid Ethyl Este;Ethyl 4-[8-chloro-5,6-dihydro-2-(hydroxy methyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-1-piperidine carboxylate;Loratadine Impurity 2;Loratadine Impurity 25;1-Piperidinecarboxylic acid, 4-[8-chloro-5,6-dihydro-2-(hydroxymethyl)-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene]-, ethyl ester | | CAS: | 609806-39-5 | | MF: | C23H25ClN2O3 | | MW: | 412.91 | | EINECS: | | | Product Categories: | Intermediates & Fine Chemicals;Pharmaceuticals;Metabolites & Impurities | | Mol File: | 609806-39-5.mol |  |
| | 2-Hydroxymethyl Loratadine Chemical Properties |
| Melting point | 76-78°C | | Boiling point | 585.5±50.0 °C(Predicted) | | density | 1.301±0.06 g/cm3(Predicted) | | storage temp. | -20°C Freezer | | solubility | Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly) | | form | Solid | | pka | 13.40±0.10(Predicted) | | color | White to Off-White |
| | 2-Hydroxymethyl Loratadine Usage And Synthesis |
| Chemical Properties | White Solid | | Uses | A usual impurity in Loratadine syrup formulations, a nonsedating-type histamine H1-receptor. Loratadine 2-Hydroxymethyl Impurity (USP). | | Definition | ChEBI: 2-Hydroxymethyl Loratadine is a benzocycloheptapyridine. |
| | 2-Hydroxymethyl Loratadine Preparation Products And Raw materials |
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