| Company Name: |
Shenzhen Nexconn Pharmatechs Ltd |
| Tel: |
+86-755-89396905 +86-15013857715 |
| Email: |
admin@nexconn.com |
| Products Intro: |
Product Name:Apelin-12 (human, bovine, mouse, rat)/(Des-Gln1)-Apelin-13 (human, bovine, mouse, rat), Preproapelin (66-77) (human, bovine, mouse, rat), Apelin Precursor (66-77) (human, bovine, mouse, rat)
CAS:229961-08-4
Purity:98% Package:1KG;10KG;50KG
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| Company Name: |
Cellmano Biotech Limited |
| Tel: |
0551-65326643 18156095617 |
| Email: |
info@cellmano.com |
| Products Intro: |
Product Name:Apelin-12 (human, bovine, mouse, rat)
(Des-Gln1)-Apelin-13 (human, bovine, mouse, rat), Apelin Precursor (66-77) (human, bovine, mouse, rat), Preproapelin (66-77) (human, bovine, mouse, rat)
CAS:229961-08-4
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H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH manufacturers
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| | H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Basic information |
| Product Name: | H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH | | Synonyms: | PREPROAPELIN (66-77) (HUMAN, BOVINE, MOUSE, RAT);RPRLSHKGPMPF;(Des-Gln1)-Apelin-13 (huMan, bovine, Mouse, rat), Apelin Precursor (66-77) (huMan, bovine, Mouse, rat), Preproapelin (66-77) (huMan, bovine, Mouse, rat);Apelin-12,(Des-Gln1)-Apelin-13;Apelin-12 (huMan, bovine, Mouse, rat)
(Des-Gln1)-Apelin-13 (huMan, bovine, Mouse, rat), Apelin Precursor (66-77) (huMan, bovine, Mouse, rat), Preproapelin (66-77) (huMan, bovine, Mouse, rat);H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH;(DES-GLN1)-APELIN-13 (HUMAN, BOVINE, MOUSE, RAT);APELIN PRECURSOR (66-77) (HUMAN, BOVINE, MOUSE, RAT) | | CAS: | 229961-08-4 | | MF: | C64H103N21O14S | | MW: | 1422.7 | | EINECS: | | | Product Categories: | Apelin receptor;peptide;Elisa Kit-Mouse Elisa Kit | | Mol File: | 229961-08-4.mol |  |
| | H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Chemical Properties |
| RTECS | CD7310000 | | storage temp. | -15°C | | form | Lyophilized powder | | color | White to off-white | | Sequence | H-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe-OH | | InChIKey | KIODTAJAFBDDGP-TZIGXLGFSA-N |
| | H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Usage And Synthesis |
| Uses | Apelin-12 is one of the most potent C-terminal fragments of the polypeptide that possesses a high affinity to orphan receptor APJ receptor. Apelin-12 is involved in the regulation of body fluid homeostasis and in the central control of feeding. Apelin-12 blocks HIV-1 entry through APJ receptor. Apelin-12 exerts neuroprotective effect[1][2][3]. | | IC 50 | HIV-1 | | References | [1] Pisarenko OI, et al. Effects of structural analogues of apelin-12 in acute myocardial infarction in rats. J Pharmacol Pharmacother. 2013;4(3):198-203. DOI:10.4103/0976-500X.114600
[2] Pisarenko OI, et al. Apelin-12 and its structural analog enhance antioxidant defense in experimental myocardial ischemia and reperfusion. Mol Cell Biochem. 2014;391(1-2):241-250. DOI:10.1007/s11010-014-2008-4
[3] Liu DR, et al. Apelin-12 exerts neuroprotective effect against ischemia-reperfusion injury by inhibiting JNK and P38MAPK signaling pathway in mouse. Eur Rev Med Pharmacol Sci. 2018;22(12):3888-3895. Liu DR, et al. Apelin-12 exerts neuroprotective effect against ischemia-reperfusion injury by inhibiting JNK and P38MAPK signaling pathway in mouse. Eur Rev Med Pharmacol Sci. 2018;22(12):3888-3895. DOI:10.26355/eurrev_201806_15273
[4] Ohno S, et al. Apelin-12 stimulates acid secretion through an increase of histamine release in rat stomachs. Regul Pept. 2012;174(1-3):71-78. DOI:10.1016/j.regpep.2011.12.002 |
| | H-ARG-PRO-ARG-LEU-SER-HIS-LYS-GLY-PRO-MET-PRO-PHE-OH Preparation Products And Raw materials |
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