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| | 4-(4-METHOXYPHENYL)PYRIMIDIN-2-AMINE Basic information |
| Product Name: | 4-(4-METHOXYPHENYL)PYRIMIDIN-2-AMINE | | Synonyms: | 4-(4-METHOXYPHENYL)PYRIMIDIN-2-AMINE;4-(4-METHOXYPHENYL)-2-PYRIMIDINAMINE;4-(4-METHOXYPHENYL)-2-PYRIMIDINYLAMINE;2-AMINO-4-(4-METHOXYPHENYL)PYRIMIDINE;BUTTPARK 16\04-19;2-ANIMO-4-(4-METHOXYPHENYL)PYRIMIDINE;[4-(4-methoxyphenyl)pyrimidin-2-yl]amine;2-PyriMidinaMine, 4-(4-Methoxyphenyl)- | | CAS: | 99844-02-7 | | MF: | C11H11N3O | | MW: | 201.22 | | EINECS: | | | Product Categories: | | | Mol File: | 99844-02-7.mol |  |
| | 4-(4-METHOXYPHENYL)PYRIMIDIN-2-AMINE Chemical Properties |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| Hazard Codes | Xi,Xn | | Risk Statements | 22 | | HazardClass | IRRITANT | | HS Code | 2933599590 |
| | 4-(4-METHOXYPHENYL)PYRIMIDIN-2-AMINE Usage And Synthesis |
| Synthesis | GENERAL METHOD: A mixture of 3-(dimethylamino)-1-(4-methoxyphenyl)prop-2-en-1-one (1 mmol), guanidine nitrate (2 mmol) and anhydrous K2CO3 (5 mmol) in n-butanol (10 mL) was refluxed for 12 hours. After completion of the reaction, it was cooled to room temperature and the reaction solution was poured into water (30 mL) and extracted with ethyl acetate (3 x 20 mL). The organic layers were combined and concentrated under reduced pressure, and the resulting crude product was purified by recrystallization from ether to give 4-(4-methoxyphenyl)pyrimidin-2-amine. | | References | [1] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 13, p. 3024 - 3028 |
| | 4-(4-METHOXYPHENYL)PYRIMIDIN-2-AMINE Preparation Products And Raw materials |
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