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| | 1-(4-Thiazolyl)-ethanone Basic information |
| Product Name: | 1-(4-Thiazolyl)-ethanone | | Synonyms: | Ethanone, 1-(4-thiazolyl)- (9CI);4-Acetylthiazole;Methyl 4-thiazolyl ketone;4-Acetylthiozole;Ethanone,1-(4-thiazolyl)-;1-(1,3-thiazol-4-yl)ethan-1-one;1-(4-Thiazolyl);1-(4-Thiazolyl)-ethanone | | CAS: | 38205-66-2 | | MF: | C5H5NOS | | MW: | 127.16 | | EINECS: | | | Product Categories: | ACETYLGROUP | | Mol File: | 38205-66-2.mol |  |
| | 1-(4-Thiazolyl)-ethanone Chemical Properties |
| Melting point | 56℃ | | Boiling point | 220℃ | | density | 1.226 | | Fp | 87℃ | | storage temp. | Sealed in dry,Room Temperature | | form | solid | | pka | 0.19±0.10(Predicted) | | color | Cream |
| | 1-(4-Thiazolyl)-ethanone Usage And Synthesis |
| Synthesis | (C) Synthesis of 1-thiazol-4-yl-ethanone (4). A mixed solution of compound 3 (2.4 g, 12.4 mmol) with 4 mL of 5% HCl in 40 mL of THF was stirred at room temperature for 1 hour. After completion of the reaction, the mixture was diluted with ether, washed sequentially with saturated NaHCO3 solution, dried over anhydrous Na2SO4, and concentrated under reduced pressure to afford 1.44 g (94% yield) of the target product 4, which was in the form of an oil and could be used in the subsequent reaction without further purification. | | References | [1] Patent: WO2004/87698, 2004, A2. Location in patent: Page 37; 50 |
| | 1-(4-Thiazolyl)-ethanone Preparation Products And Raw materials |
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