AP39
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- $32 - $1240
- Product name: AP39
- CAS: 1429173-57-8
- MF: C37H38O2PS3+
- MW: 641.865
- EINECS:
- MDL Number:MFCD00947997
- Synonyms:AP39;AP39 Free base
6 prices
Selected condition:
Brand
- AK Scientific
- Cayman Chemical
- TRC
Package
- 1mg
- 5mg
- 10mg
- 25mg
- 100mg
- ManufacturerAK Scientific
- Product number9245DU
- Product description[10-Oxo-10-[4-(5-sulfanylidenedithiol-3-yl)phenoxy]decyl]-triphenylphosphanium
- Packaging1mg
- Price$133
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number17100
- Product descriptionAP39 ≥95%
- Packaging25mg
- Price$533
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17100
- Product descriptionAP39 ≥95%
- Packaging10mg
- Price$243
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17100
- Product descriptionAP39 ≥95%
- Packaging5mg
- Price$139
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number17100
- Product descriptionAP39 ≥95%
- Packaging1mg
- Price$32
- Updated2024-03-01
- Buy
- ManufacturerTRC
- Product numberA729260
- Product descriptionAP39
- Packaging100mg
- Price$1240
- Updated2021-12-16
- Buy
Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|
AK Scientific | 9245DU | [10-Oxo-10-[4-(5-sulfanylidenedithiol-3-yl)phenoxy]decyl]-triphenylphosphanium | 1mg | $133 | 2021-12-16 | Buy |
Cayman Chemical | 17100 | AP39 ≥95% | 25mg | $533 | 2024-03-01 | Buy |
Cayman Chemical | 17100 | AP39 ≥95% | 10mg | $243 | 2024-03-01 | Buy |
Cayman Chemical | 17100 | AP39 ≥95% | 5mg | $139 | 2024-03-01 | Buy |
Cayman Chemical | 17100 | AP39 ≥95% | 1mg | $32 | 2024-03-01 | Buy |
TRC | A729260 | AP39 | 100mg | $1240 | 2021-12-16 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMF: 5 mg/ml; DMSO: 20 mg/ml; Ethanol: 16 mg/ml; PBS (pH 7.2): 1 mg/ml
solubility :DMF: 5 mg/ml; DMSO: 20 mg/ml; Ethanol: 16 mg/ml; PBS (pH 7.2): 1 mg/ml
Safety Information
Symbol(GHS): |
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Description
AP39 is a compound used to increase the levels of hydrogen sulfide (H2S) within mitochondria. It consists of a mitochondria-targeting motif (triphenylphosphonium) coupled to an H2S-donating moiety (dithiolethione) by an aliphatic linker. AP39 (30-300 nM) dose-dependently increases H2S levels in endothelial cells, predominantly in mitochondrial regions. It stimulates mitochondrial electron transport and improves cellular bioenergetic function at lower concentrations (30-100 nM), while having an inhibitory effect at 300 nM. Under oxidative stress conditions induced by glucose oxidase, AP39 has antioxidant and cytoprotective effects. AP39 is effective in vivo, inhibiting voltage-dependent T-type calcium channels and improving hemodynamic parameters in rats.Suppliers and manufacturers
BOC Sciences
Shanghai EFE Biological Technology Co., Ltd.
Shanghai Hongye Biotechnology Co. Ltd
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
MedBioPharmaceutical Technology Inc
TargetMol Chemicals Inc.
Meryer (Shanghai) Chemical Technology Co., Ltd.
Shanghai Yiyan Biotechnology Co. , Ltd.
Cayman Chemical Company
Biosynth Biological Technology (Suzhou) Co Ltd