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(S)-2-?????????(???)

(S)-2-?????????(???)
(S)-2-?????????(???) ??? ???
?? ??:
188398-87-0
???:
(S)-2-?????????(???)
???(??):
(S)-2-?????????(???)
???:
(S)-2-Diphenylmethylpyrrolidine (hydrochloride)
???(??):
(S)-Desoxy-D2PM (hydrochloride);(S)-2-Benzhydrylpyrrolidinehydrochloride;(S)-2-Diphenylmethylpyrrolidine (hydrochloride);Pyrrolidine, 2-(diphenylmethyl)-, hydrochloride (1:1), (2S)-;(2S)-2-(Diphenylmethyl)pyrrolidine Hydrochloride (1.0 mg/mL in Methanol)
CBNumber:
CB82589831
???:
C17H20ClN
??? ??:
273.8004
MOL ??:
188398-87-0.mol

(S)-2-?????????(???) ??

???
281-282 °C(Solv: dichloromethane (75-09-2); ligroine (8032-32-4))
???
DMF: 30 mg/ml; DMSO: 30 mg/ml; Ethanol: 20 mg/ml; Methanol: 1 mg/ml; PBS (pH 7.2): 20 mg/ml
??? ??
??? ??
InChI
InChI=1/C17H19N.ClH/c1-3-8-14(9-4-1)17(16-12-7-13-18-16)15-10-5-2-6-11-15;/h1-6,8-11,16-18H,7,12-13H2;1H/t16-;/s3
InChIKey
KTGRJTGIWVDSKZ-LSQUZMQTNA-N
SMILES
N1CCC[C@H]1C(C1=CC=CC=C1)C1=CC=CC=C1.[H]Cl |&1:4,r|

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(S)-2-?????????(???) C??? ??, ??, ??

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(S)-Desoxy-D2PM (hydrochloride) is most commonly used as a chiral solvating agent for NMR analysis of chiral compounds. Interestingly, it is also, structurally, closely related to 2-DPMP (hydrochloride) , a dopamine transporter inhibitor and psychoactive stimulant. The physiological and toxicological properties of (S)-Desoxy-D2PM have not been explored.

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The hydrochloride salt of a useful chiral auxiliary (2S)-2-(Diphenylmethyl)pyrrolidine, based on (S)-proline and bearing sterically demanding side chains at the pyrrolidine moiety.

(S)-2-?????????(???) ?? ?? ? ???

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