2-(Tributylstannyl)pyrimidine
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2-(Tributylstannyl)pyrimidine ??
- ?? ?
- 381.2±25.0 °C(Predicted)
- ??
- 1.164 g/mL at 25 °C
- ???
- n20/D1.512
- ???
- >110℃
- ?? ??
- Sealed in dry,2-8°C
- ???
- soluble in Methanol; Ethyl Acetate; Dichloromethane; Chloroform; DMF; DMSO
- ??? ??
- ??
- ?? ?? (pKa)
- 1.42±0.33(Predicted)
- ??
- ??
- InChI
- InChI=1S/C4H3N2.3C4H9.Sn/c1-2-5-4-6-3-1;3*1-3-4-2;/h1-3H;3*1,3-4H2,2H3;
- InChIKey
- WTFFOOAJSDVASL-UHFFFAOYSA-N
- SMILES
- C1([Sn](CCCC)(CCCC)CCCC)=NC=CC=N1
??
- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| ??? ?? | Xi,T,N | ||
|---|---|---|---|
| ?? ???? ?? | 21-25-36/38-48/23/25-50/53 | ||
| ????? | 36/37/39-45-60-61-35 | ||
| ????(UN No.) | UN 2788 6.1 / PGIII | ||
| WGK ?? | 3 | ||
| ?? ?? | IRRITANT, TOXIC, KEEP COLD | ||
| HS ?? | 29339900 |
| ????(GHS): |
  
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| ?? ?: | Danger | |||||||||||||||||||||||||||||||||||||||||||||||||
| ??·?? ??: |
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2-(Tributylstannyl)pyrimidine C??? ??, ??, ??
??? ??
Clear colorless liquid??
2-(Tributylstannyl)pyrimidine is an organotin compound used in Stille coupling reaction. This can be used as one of the precursors in the synthesis of 2-aminopyridine oxazolidinones as potent and selective tankyrase (TNKS) inhibitors and the synthesis of canagliflozin, a novel inhibitor for sodium-dependent glucose cotransporter.It can also be used in the preparation of various (2-pyrimidyl)silanes.
2-(Tributylstannyl)pyrimidine ?? ?? ? ???
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?? ???
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2-Chloropyrimidine
????
Lithium diisopropylamide
?? ??
2-(Tributylstannyl)pyrimidine ?? ??
???( 120)?? ??
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|---|---|---|---|---|---|
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