ChemicalBook >?? ???? >??? ??>??????? ? >? ??? ?? ???>4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI)

4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI)

4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) ??? ???

?? ??:: 65996-58-9

???:: 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI)

???(??):: NSC 344522;9-deazaguanine;2-amino-3H-pyrrolo[3,2-d]pyrimidin-4(5H)-one;2-amino-1H-pyrrolo[3,2-d]pyrimidin-4(5H)-one;2-amino-1,5-dihydropyrrolo[3,2-d]pyrimidin-4-one;2-Amino-3,5-dihydropyrrolo[3,2-D]pyrimidine-4-one;2-AMINO-3,5-DIHYDRO-PYRROLO[3,2-D]PYRIMIDIN-4-ONE;2-amino-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one;2-Amino-1,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one;4H-Pyrrolo3,2-dpyrimidin-4-one, 2-amino-1,5-dihydro-

CBNumber:: CB81081820

???:: C6H6N4O

??? ??:: 150.14

MOL ??:: 65996-58-9.mol

?? ?? 87

4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) ??

???: >300 °C(Solv: water (7732-18-5))

??: 1.87±0.1 g/cm3(Predicted)

?? ??: Keep in dark place,Sealed in dry,2-8°C

???: DMSO(?? ???), ???(?? ???, ??)

?? ?? (pKa): 10.85±0.20(Predicted)

??? ??: ??

??? ??: ??? ??

??: ????

?? ? ?? ??
?? ? ???? ?? (GHS)

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H226	??? ?? ? ??	??? ??	?? 3	??
H302	??? ???	?? ?? ?? - ??	?? 4	??	P264, P270, P301+P312, P330, P501
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??	P264, P280, P305+P351+P338,P337+P313P
H373	??? ?? ?? ???? ??(??, ??? ?? ??? ?? ??? ??)? ??? ??? ? ??	?? ???? ?? - ?? ??	?? 2	??	P260, P314, P501

??????:

P210	?·???·??·????? ????? - ?? ???.
P233	??? ??? ?????. ??? ??? ? ?? ?? ??? ???? ?????.
P240	??? ????? ?? ? ??????.
P241	?? ??? ??[???/??/??/...]?(?) ?????.
P242	???? ???? ?? ??? ?????
P243	??? ?? ??? ????.
P260	??·?·??·???·??·...·????? ???? ???.
P264	?? ??? ?? ??? ????.
P264	?? ??? ?? ??? ????.
P270	? ??? ??? ??? ???, ???? ???? ???.
P280	????/???/???/?????? ?????.
P303+P361+P353	??(?? ????)? ??? ??? ?? ??? ??? ????? ??? ?? ????/?????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P314	???? ??? ???? ??·??? ????.
P332+P313	?? ??? ??? ???? ??· ??? ????.
P337+P313	?? ?? ??? ???? ???? ??· ??? ????.
P370+P378	?? ? ?? ?? ?? (Section 5. ??, ??? ????? ??? ???)?(?) ?????.
P403+P235	??? ? ?? ?? ???? ???? ?????.
P501	...? ??? / ??? ?? ???.

NFPA 704

	0
2		0

4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) C??? ??, ??, ??

??

9-Deazaguanine is an analog of guanine that acts as an inhibitor of purine nucleoside phosphorylase (PNP; K_d = 160 nM). Inhibitors of PNP are used to control T cell proliferation, particularly in T cell cancers, autoimmune diseases, and tissue transplant rejection.

??? ??

Beige Solid

??

A nucleoside analog as potent inhibitor of purine nucleoside phosphorylase.

4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) ?? ?? ? ???

???

Methanimidamide, N'-(4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-2-yl)-N,N-dimethyl- Methanimidamide, N'-[4-[(1E)-2-(dimethylamino)ethenyl]-1,6-dihydro-5-nitro-6-oxo-2-pyrimidinyl]-N,N-dimethyl- 1,3-Bis(methoxycarbonyl)-2-methyl-2-thiopseudoeura 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-3,5-dihydro-3-(phenylmethyl)- 1H-??-2-?????,3-???-,?????? ???? ??????

?? ??

7-DEAZAGUANOSINE

4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) ?? ??

???( 87)?? ??

???	??	???	??	?? ?	??
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4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) ?? ??:

4H-Pyrrolo[2,3-d]pyrimidin-4-one, 2-amino-1,7-dihydro- (9CI) 2H-Pyrrolo[2,3-d]pyrimidin-2-one, 4-amino-1,7-dihydro- (9CI) 6H-Pyrrolo[3,2-d]pyrimidin-6-one, 4-amino-5,7-dihydro- (9CI) 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 7-amino-1,5-dihydro- (9CI) 9-DEAZA-2'-DEOXYGUANOSINE (2-AMINO-7-(BETA-D-2-DEOXYRIBOFURANOSYL)PYRROLO[3,2-D]PYRIMIDIN-4-ONE) 9-deaza-9-(3-thienylmethyl)guanine CI 972 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-amino-1,5-dihydro- (9CI) 5'-O-(4,4'-DIMETHOXYTRITYL)-N2-DIMETHYLAMINOMETHYLENE-7-DEAZA-2'-DEOXYGUANOSINE, 3'-[(2-CYANOETHYL)-(N,N-DIISOPROPYL)]PHOSPHORAMIDITE Peldesine

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