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17-?????????????

17-?????????????
17-????????????? ??? ???
?? ??:
64202-81-9
???:
17-?????????????
???(??):
17-?????????????
???:
17-Aminodemethoxygeldanamycin
???(??):
IPI-493;NSC 255109;17-Aminogeldanamycin;Geldanamycin 17-Amino;17-Amino Geldanamycin;17-Aminodemethoxygeldanamycin;17-Amino-17-demethoxygeldanamycin;Geldanamycin, 17-amino-17-demethoxy-;17-Aminodemethoxygeldanamycin|||17-Aminogeldanamycin|||IPI 493|||NSC 255109|||17-amino17demethoxy
CBNumber:
CB71238764
???:
C28H39N3O8
??? ??:
545.62
MOL ??:
64202-81-9.mol

17-????????????? ??

???
178-180°C
?? ?
777.8±60.0 °C(Predicted)
??
1.25±0.1 g/cm3(Predicted)
?? ??
Refrigerator
???
?????, ???? ???
??? ??
??
??? ??
??? ??
?? ?? (pKa)
8.59±0.70(Predicted)
??
??? ???

??

17-????????????? C??? ??, ??, ??

??? ??

Dark Purple Solid

??

The active metabolite of 17-(Allylamino)geldanamycin (17AAG).

17-????????????? ?? ?? ? ???

???

Geldanamycin

?? ??

17-????????????? ?? ??

???( 24)?? ??
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17-????????????? ?? ??:

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