ChemicalBook >?? ???? >5-Chloro-6'-Methyl-3-[4-(Methylsulfonyl)phenyl]-2,3'-bipyridine 1'-Oxide

5-Chloro-6'-Methyl-3-[4-(Methylsulfonyl)phenyl]-2,3'-bipyridine 1'-Oxide

5-Chloro-6'-Methyl-3-[4-(Methylsulfonyl)phenyl]-2,3'-bipyridine 1'-Oxide ??? ???

?? ??:: 325855-74-1

???:: 5-Chloro-6'-Methyl-3-[4-(Methylsulfonyl)phenyl]-2,3'-bipyridine 1'-Oxide

???(??):: Etoricoxib K;Etoricoxib N-Oxide;5-chloro-6'-methyl-3;Etoricoxib N1'-Oxide;Etoricoxib N1′-Oxide, CAS 325855-74-1;Etoricoxib n-oxide / Etoricoxib EP Impurity-F;5-chloro-6'-methyl-3-(4-(methylsulfonyl)phenyl);5-Chloro-6'-Methyl-3-[4-(Methylsulfonyl)phenyl]-2,3'-bipyridine 1'-Oxide;5-chloro-2-(6-methyl-1-oxidopyridin-1-ium-3-yl)-3-(4-methylsulfonylphenyl)pyridine;5-Chloro-6'-methyl-3-(4-(methylsulfonyl)phenyl)-[2,3'-bipyridine] 1'-oxide (Etoricoxib Impurity)

CBNumber:: CB62622662

???:: C18H15ClN2O3S

??? ??:: 374.84

MOL ??:: 325855-74-1.mol

?? ?? 82

5-Chloro-6'-Methyl-3-[4-(Methylsulfonyl)phenyl]-2,3'-bipyridine 1'-Oxide ??

???: 204-206°C

?? ?: 603.5±55.0 °C(Predicted)

??: 1.35±0.1 g/cm3(Predicted)

?? ??: Sealed in dry,Store in freezer, under -20°C

???: ?????(?? ???), DMSO(?? ???, ?????), ???(?? ???, ??)

??? ??: ??

??? ??: ??? ??

?? ?? (pKa): 0.25±0.10(Predicted)

??: ???? ?????

?? ? ?? ??
?? ? ???? ?? (GHS)

????(GHS):

?? ?:

Warning

??·?? ??:

??	??·?? ??	?? ??	??	?? ?	P- ??
H302	??? ???	?? ?? ?? - ??	?? 4	??	P264, P270, P301+P312, P330, P501
H315	??? ??? ???	????? ?? ?????	?? 2	??	P264, P280, P302+P352, P321,P332+P313, P362
H319	?? ?? ??? ???	?? ? ?? ?? ??? ??	?? 2A	??	P264, P280, P305+P351+P338,P337+P313P
H335	?? ???? ??? ? ??	?? ???? ?? - 1? ??;???? ??	?? 3	??

??????:

P261	??·?·??·???·??·...·????? ??? ????.
P305+P351+P338	?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.

5-Chloro-6'-Methyl-3-[4-(Methylsulfonyl)phenyl]-2,3'-bipyridine 1'-Oxide C??? ??, ??, ??

??

Etoricoxib N1’Oxide is an impurity of Etoricoxib (E934100).

5-Chloro-6'-Methyl-3-[4-(Methylsulfonyl)phenyl]-2,3'-bipyridine 1'-Oxide ?? ?? ? ???

???

Etoricoxib 1-(6-Methylpyridin-3-yl)-2-(4-(methylsulfonyl)phenyl)ethanone

?? ??

5-Chloro-6'-Methyl-3-[4-(Methylsulfonyl)phenyl]-2,3'-bipyridine 1'-Oxide ?? ??

???( 82)?? ??

???	??	???	??	?? ?	??
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5-Chloro-6'-Methyl-3-[4-(Methylsulfonyl)phenyl]-2,3'-bipyridine 1'-Oxide ?? ??:

(Z)-1-(6-methylpyridin-3-yl)-2-(4-(methylsulfonyl)phenyl)ethanone oxime (E)-2-chloro-3-iMino-N,N-diMethylprop-1-en-1-aMine hydrochloride Etoricoxib Impurity 11 lithiuM 2-(4-(Methylsulfonyl)phenyl)acetate Etoricoxib Etoricoxib IMpurity EtoMidate IMpurity C HCl Etoricoxib Impurity 13 3 aMino-2-chloroacrolein Etoricoxib Impurity 7 4-(METHYLSULFONYL)PHENYLACETONITRILE Etoricoxib Impurity 18 Etoricoxib Impurity 38 Etoricoxib iMpurity 2 Etoricoxib Impurity 16 Etoricoxib Impurity 19 Etoricoxib impurity 22 Etoricoxib iMpurity 1

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