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???????????
??????????? ??? ???
?? ??:
501-52-0
???:
???????????
???(??):
???????????;3-???????
???:
3-Phenylpropionic acid
???(??):
HYDROCINNAMIC ACID;3-PHENYLPROPANOIC ACID;BENZENEPROPANOIC ACID;HYDROXYCINNAMIC ACID;Phenylpropanoic acid;Benzenepropionic acid;NSC 9272;LABOTEST-BB LT00014254;3 - styrene acrylic acid;3-Phenyl-n-propionic acid
CBNumber:
CB6230832
???:
C9H10O2
??? ??:
150.17
MOL ??:
501-52-0.mol
MSDS ??:
SDS

??????????? ??

???
45-48 °C (lit.)
?? ?
280 °C (lit.)
??
1.071 g/mL at 25 °C (lit.)
???
0.356Pa at 25℃
FEMA
2889 | 3-PHENYLPROPIONIC ACID
???
1.5408 (estimate)
???
>230 °F
?? ??
Sealed in dry,Room Temperature
???
???: ???50mg/mL, ??, ?? ?? ??? ???
??? ??
??
?? ?? (pKa)
4.66(at 25℃)
Specific Gravity
1.071
??
??? ????? ?????
??
????? ??? ? 1.00%. ??? ?? ?? ??? ??
?? ??
???
???? ??
synthetic
???
?? ???
JECFA Number
646
Merck
14,4784
BRN
907515
InChIKey
XMIIGOLPHOKFCH-UHFFFAOYSA-N
LogP
1.153 at 25℃
CAS ??????
501-52-0(CAS DataBase Reference)
NIST
3-Phenylpropanoic acid(501-52-0)
EPA
Hydrocinnamic acid (501-52-0)
??
  • ?? ? ?? ??
  • ?? ? ???? ?? (GHS)
??? ?? Xi
?? ???? ?? 36/37/38
????? 22-24/25-37/39-26
WGK ?? 3
RTECS ?? DA8600000
TSCA Yes
HS ?? 29163900
????(GHS): GHS hazard pictograms
?? ?: Warning
??·?? ??:
?? ??·?? ?? ?? ?? ?? ?? ? ?? ?? P- ??
H315 ??? ??? ??? ????? ?? ????? ?? 2 ?? GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 ?? ?? ??? ??? ?? ? ?? ?? ??? ?? ?? 2A ?? GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 ?? ???? ??? ? ?? ?? ???? ?? - 1? ??;???? ?? ?? 3 ?? GHS hazard pictograms
??????:
P261 ??·?·??·???·??·...·????? ??? ????.
P304+P340 ???? ??? ??? ?? ??? ??? ???? ?? ??? ??? ????.
P305+P351+P338 ?? ??? ? ?? ?? ???? ????. ???? ?????? ?????. ?? ????.
P405 ???? ?????.
NFPA 704
0
0 0

??????????? MSDS


beta-Phenylpropionic acid

??????????? C??? ??, ??, ??

??? ??

3-Phenylpropionic acid has a faint, sweet odor, somewhat balsamic and coumarin-like with a mildly sweet-sour, vanilla-like taste.

??

Reported found in raspberry, guava fruit, Vitis vinifera L., papaya, strawberry fruit, cinnamon, cassia leaf, cheddar cheese, cocoa, beer, cognac, white wine, red wine, special wine, rose apple, mushroom, cloudberry, Boletus edulis, fresh mango, licorice and labdanum.

??

Used in the compositions for the treatment of blood disorders using α-methylhydrocinnamic acid.
Hydrocinnamic acid was used in the synthesis of three medium-chain acyl-Coenzyme A′s i.e. 3-phenylpropionyl-CoA from mixed anhydrides of fatty acids.

?? ??

By reduction of cinnamic acid using sodium amalgam.

??

ChEBI: A monocarboxylic acid that is propionic acid substituted at position 3 by a phenyl group.

?? ??

Hydrocinnamic acid forms complexes with uranium(VI) and has been investigated in aqueous solution by attenuated total reflection fourier transform infrared spectroscopy. Hydrocinnamic acids are the major rhizospheric compounds with known growth regulatory activity.

Purification Methods

Crystallise the acid from *benzene, CHCl3 or pet ether (b 40-60o). Dry it in a vacuum. [Beilstein 9 H 508.]

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