ChemicalBook >?? ???? >2-?????????
2-?????????
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2-????????? ??
- ???
- 114 °C(Solv: chloroform (67-66-3))
- ?? ?
- 376.7±25.0 °C(Predicted)
- ??
- 1.578±0.06 g/cm3(Predicted)
- ?? ??
- under inert gas (nitrogen or Argon) at 2-8°C
- ???
- ???,DMSO? ???
- ??? ??
- powder to crystal
- ?? ?? (pKa)
- 3.31±0.10(Predicted)
- ??
- ???? ?? ??
- InChI
- InChI=1S/C6H5NO4/c8-4-1-2-5(9)7(4)3-6(10)11/h1-2H,3H2,(H,10,11)
- InChIKey
- GBKPNGVKZQBPCZ-UHFFFAOYSA-N
- SMILES
- N1(CC(O)=O)C(=O)C=CC1=O
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- ?? ? ?? ??
- ?? ? ???? ?? (GHS)
| HS ?? | 2925.19.4200 |
|---|
2-????????? C??? ??, ??, ??
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White to Almost white powder to crystal or Pale Yellow Solid.??
Maleimidoacetic Acid (CAS# 25021-08-3) is a heterocyclic organic compound that has a variety of uses in organic synthesis. It contains both a maleimide and carboxylic acid functional group, making it a versatile reagent for coupling reactions with amine-containing compounds.?? ??
2-Maleimido acetic acid is a maleimide-containing ligand that could be used to produce the cisplatin-based Pt(IV) complexes (OC-6-44)-diamminedichlorido(ethanolato)(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetato)platinum(IV) and (OC-6-44)-acetatodiamminedichlorido(2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetato)platinum(IV). The Pt(IV) complexes are considered to act as antitumor prodrugs and their in vivo activity can be improved by exploiting drug targeting and delivery strategies[1]. In this case, conjugation between maleimide-containing Pt(IV) prodrugs and furan or furan-containing drug delivery vectors via Diels-Alder cycloaddition.2-????????? ?? ?? ? ???
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2-????????? ?? ??
???( 146)?? ??
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2-????????? ?? ??:
DISUCCINIMIDYL SUBERATE
Suberate Bis(sulfosuccinimidyl) Sodium Salt
N-Succinimidyl maleimidoacetate
3-(BENZOPHENONE-4-CARBOXAMIDO)-2-MALEIMIDOPROPANOIC ACID
2-Maleimido acetic acid
2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methanesulfonylbutanoic acid
2-(2,5-DIOXO-2,5-DIHYDRO-PYRROL-1-YL)-PROPIONIC ACID
2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-phenylpropanoic acid
2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-methylbutanoic acid
DACM
3-MALEIMIDO-4-METHYL-6,7-METHYLENEDIOXYCOUMARIN
RARECHEM AL CD 0491
4-carbamoyl-2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)butanoic acid
2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-methylpentanoic acid
9-ACETOXY-2-(4-(2,5-DIHYDRO-2,5-DIOXO-1H-PYRROL-1-YL)-3-OXO-3-H-NAPHTHO[2,1-B]PYRAN
2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-3-(1H-imidazol-4-yl)propanoic acid
2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-4-methylpentanoic acid
methyl 2-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)acetate