ChemicalBook >?? ???? >PSB-12379
PSB-12379
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PSB-12379 ??
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- 894.2±75.0 °C(Predicted)
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- 1.89±0.1 g/cm3(Predicted)
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- Store at -20°C
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- Water: 5 mg/ml, sonicated
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- ?? ?? (pKa)
- 1.62±0.10(Predicted)
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- White to off-white
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- H2O: 2mg/mL, clear
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PSB-12379 C??? ??, ??, ??
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PSB-12379 is an inhibitor of ecto-5’-nucleotidase (CD73; Kis = 2.21 and 9.03 nM for the recombinant human and rat enzyme, respectively). It is selective for CD73 over human nucleoside triphosphate diphosphohydrolase 1 (NTPDase 1), -2, and -3, ectonucleotide pyrophosphatase/phosphodiesterase family member 1 (ENPP1), -2, and -3 (Kis = >10,000 nM for all), as well as the purinergic P2Y1 and P2Y12 receptors at 10 μM. PSB-12379 inhibits CD73 in isolated human serum with a Ki value of 18.8 nM.PSB-12379 ?? ?? ? ???
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PSB-12379 ?? ??
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| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +17819995354 |
marketing@targetmol.com | United States | 32371 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 |
liming@bio-fount.com | China | 9729 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 |
sales@chemegen.com | China | 11218 | 58 |
| Shanghai hongqu biomedical technology co. LTD | 88888888888 |
hongquchem@qq.com | China | 5132 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223; |
psaitong@jm-bio.com | China | 29770 | 58 |
| Kaifeng Mingren Pharmaceutical Co.,LTD | 0371-65741762 |
sales@hasunny.com | China | 2380 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 |
customer_service@efebio.com | China | 11973 | 58 |
| RD International Technology Co., Limited | 18024082417 |
market@ubiochem.com | China | 9835 | 58 |
| Changzhou Yourui Pharmaceutical Technology Co., Ltd | 18168818882 |
877458914@qq.com | China | 3242 | 58 |
| R&D Systems, Inc | 18003437475 |
rdname@qq.com | China | 6960 | 58 |