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????????????????? ??? ???
?? ??:
40732-48-7
???:
?????????????????
???(??):
?????????????????
???:
GUANOSINE 3':5'-CYCLIC MONOPHOSPHATE SODIUM SALT
???(??):
CGMP NA;G-3,5-MP;3',5'-CGMP NA;MonosodiuM-GMP;CGMP SODIUM SALT;Cyclic GMP (sodium);G-3,5-MP SODIUM SALT;GUANOSINE 3':5'-CYCL;CYCLIC GMP SODIUM SALT;cGMP sodium salt - Bio-X ?
CBNumber:
CB5302819
???:
C10H13N5NaO7P
??? ??:
369.21
MOL ??:
40732-48-7.mol
MSDS ??:
SDS

????????????????? ??

???
>240°C (dec.)
?? ??
-20°C
???
H2O: 50 mg/mL
??? ??
??
??
???
???
water: 1mg/mL
BRN
6467425
InChIKey
HLNMNLSGNGHULD-NGPBCCOENA-N
SMILES
O=C1NC(N)=NC2N([C@@H]3O[C@]4([H])COP(O)(=O)O[C@@]4([H])[C@H]3O)C=NC1=2.[NaH] |&1:8,10,18,20,r|

??

WGK ?? 3
F ?????? 10-21
HS ?? 29349990

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White powder

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Guanosine 3’,5’-Cyclic Monophosphate is a substituted Guanosine having cyclic phosphodiesterase activity.

Biochem/physiol Actions

An important second messenger, cGMP is a major intracellular mediator of extracellular signals such as nitric oxide and natriuretic peptides. Cyclic GMP interacts with three types of intracellular receptor proteins: cGMP-dependent protein kinases, cGMP-regulated channels, and cGMP-regulated cyclic nucleotide phosphodiesterases. A primary action of elevated cGMP levels in vivo is the stimulation of cGMP-dependent protein kinase (PKG).

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