23-HYDROXYBETULINIC ACID
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23-HYDROXYBETULINIC ACID ??
- ???
- >293°C (dec.)
- ?? ?
- 585.8±25.0 °C(Predicted)
- ??
- 1.106
- ?? ??
- -20°C Freezer, Under inert atmosphere
- ???
- ???(??, ??), ???(??)? ???
- ??? ??
- ??
- ??? ??
- ??? ??
- ?? ?? (pKa)
- 4.60±0.70(Predicted)
- ??
- ???
- InChIKey
- HXWLKAXCQLXHML-WGOZWDAUSA-N
- SMILES
- C([C@]12CC[C@H]([C@]1([H])[C@@]1([H])CC[C@]3([H])[C@]4(CC[C@@H]([C@@]([C@]4([H])CC[C@]3([C@@]1(CC2)C)C)(C)CO)O)C)C(=C)C)(=O)O
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23-HYDROXYBETULINIC ACID C??? ??, ??, ??
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23-hydroxy Betulinic acid is a triterpenoid that has been found in P. chinensis and has anticancer activity. It inhibits proliferation of K562, B16, and HeLa cells (IC50s = 39.9, 78.5, and 80 μM, respectively), as well as human umbilical vein endothelial cells (HUVECs; IC50 = 94.8 μM). It halts the cell cycle at the S phase and induces apoptosis in K562 cells in a concentration-dependent manner with a loss of the mitochondrial membrane potential and an increase in Bax and cytochrome C protein levels.??
23-Hydroxybetulinic Acid is a potential cytoxic agent in the treatment of cancer. Apoptotic effect. Antiproliferative.23-HYDROXYBETULINIC ACID ?? ?? ? ???
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23-HYDROXYBETULINIC ACID ?? ??
???( 154)?? ??
| ??? | ?? | ??? | ?? | ?? ? | ?? |
|---|---|---|---|---|---|
| Shaanxi Haibo Biotechnology Co., Ltd | +undefined18602966907 |
qinhe02@xaltbio.com | China | 997 | 58 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 |
zheyansh@163.com | CHINA | 3619 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 |
scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-28-82633860; +8618080483897 |
sales@biopurify.com | China | 3751 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28172 | 58 |
| NanJing Spring & Autumn Biological Engineering CO., LTD. | +8613815430202 |
sale02@cqherb.com | CHINA | 376 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
factory@coreychem.com | China | 29804 | 58 |
| Wuhan ChemNorm Biotech Co.,Ltd. | +86-27-8439 4403 18971486879 |
sales@chemnorm.com | CHINA | 2935 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354; +17819995354 |
marketing@targetmol.com | United States | 32376 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 |
ada@ipurechemical.com | China | 10244 | 58 |
23-HYDROXYBETULINIC ACID ?? ??:
Ethylparaben
Betulinicaldehyde
Pachymic acid
Poricoic acid A(F)
Madecassoside
Terrestrosin D
Betulinic acid
3-Oxo-olean-12-en-28-oic acid
Ursonic acid
Terrestrosin K
Betulin
dipotassium dihydrogen 15alpha-hydroxy-2beta-[[2-O-isovaleryl-3,4-di-O-sulphonato-beta-D-glucopyranosyl]oxy]kaur-16-ene-18,19-dioate
roburic acid
Epibetulinic acid
Carboxyatractyloside
Madecassic acid
ALLEOSIDE A
Calcium hydroxyphosphate