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??? ????

??? ????
??? ???? ??? ???
?? ??:
50-41-9
???:
??? ????
???(??):
???????;???????
???:
Clomiphene Citrate
???(??):
CLOMID;CLOMIFENE CITRATE;clomifeno;CloMifene Citrate Capsules;SEROPHENE;mer41;mrl41;fertyl;omifin;dyneric
CBNumber:
CB0488051
???:
C32H36ClNO8
??? ??:
598.08
MOL ??:
50-41-9.mol
MSDS ??:
SDS

??? ???? ??

???
116.5-118°C
?? ??
2-8°C
???
??? ?? ????, ????? ?? ???? ????(96%).
??? ??
Solid
??
???? ?????
???
?, ???, ?????(??) ? DMSO(10mM)? ?? ?????. ???? ???.
BCS Class
3/1
InChIKey
PYTMYKVIJXPNBD-OQKDUQJOSA-N
SMILES
N(CC)(CC)CCOC1=CC=C(/C(/C2=CC=CC=C2)=C(\Cl)/C2=CC=CC=C2)C=C1.C(O)(=O)CC(CC(O)=O)(C(O)=O)O
CAS ??????
50-41-9(CAS DataBase Reference)
IARC
3 (Vol. 21, Sup 7) 1987
EPA
Clomiphene citrate (50-41-9)

??

??? ?? T
?? ???? ?? 60-63
????? 53-36/37-45
WGK ?? 3
RTECS ?? YE0875000
?? ?? IRRITANT
HS ?? 2922190900
?? LD50 oral in rat: 5750mg/kg
???? ?? KE-05645

??? ???? C??? ??, ??, ??

??? ??

White crystalline powder with a melting point range of 116.5-118°C. It has slight solubility in ethanol, chloroform, and water, but is insoluble in ether.

??

Clomiphene Citrate is an unducer of ovulation. It is a selective estrogen receptor modulator, which acts by inhibiting the action of estrogen on the pituitary. Clomiphene Citrate is also an activator of PKC and Gonad-stimulating principle.

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