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LY379268

LY379268 化學構(gòu)造式
191471-52-0
CAS番號.
191471-52-0
化學名:
LY379268
別名:
LY379268
英語名:
LY 379268
英語別名:
CS-1087;LY397268;LY 379268;LY 379268, Group II mGlu agonist;(1R,4R,5S,6R)-4-Amino-2-oxabicyclo[3.1.0]hexane-4,6-dicarboxylicacid;2-Oxabicyclo[3.1.0]hexane-4,6-dicarboxylicacid,4-amino-,(1R,4R,5S,6R)-
CBNumber:
CB5841046
化學式:
C7H9NO5
分子量:
187.15
MOL File:
191471-52-0.mol

LY379268 物理性質(zhì)

沸點 :
413.9±45.0 °C(Predicted)
比重(密度) :
1.716±0.06 g/cm3(Predicted)
貯蔵溫度 :
Store at +4°C
溶解性:
Soluble in H2O or NaOH
外見 :
solid
酸解離定數(shù)(Pka):
1.81±0.40(Predicted)
色:
White
水溶解度 :
Soluble to 20 mM in water and to 100 mM in 1eq. NaOH

安全性情報

LY379268 価格 もっと(2)

メーカー 製品番號 製品説明 CAS番號 包裝 価格 更新時間 購入
富士フイルム和光純薬株式會社(wako) W01TOC2453 LY379268
LY 379268
191471-52-0 10mg ¥138000 2024-03-01 購入
富士フイルム和光純薬株式會社(wako) W01TOC2453 LY379268
LY 379268
191471-52-0 50mg ¥415000 2021-03-23 購入

LY379268 化學特性,用途語,生産方法

使用

LY 379268 is a group II metabotropic glutamate receptors (mGlu2/3) receptor agonist (1,2). Studies have shown that LY379268 significantly attenuated cocaine-induced increases in DA in nonhuman primates.

生物活性

Highly selective group II mGlu receptor agonist (EC 50 values are 2.69 and 4.48 nM for hmGlu 2 and hmGlu 3 respectively) that displays > 80-fold selectivity over group I and group III receptors. Provides protection against NMDA-mediated cell death in vitro and offers almost complete protection against CA1 hippocampal damage following global ischemia in gerbils. Orally and systemically active.

LY379268 上流と下流の製品情報

原材料

準備製品


LY379268 生産企業(yè)

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