3Β-HYDROXY-7-OXO-5-CHOLESTENOIC ACID
- CAS No.
- 1246298-64-5
- Chemical Name:
- 3Β-HYDROXY-7-OXO-5-CHOLESTENOIC ACID
- Synonyms
- 3Β-HYDROXY-7-OXO-5-CHOLESTENOIC ACID;3ss-hydroxy-7-oxo-5-cholestenoic acid;3β-hydroxy -7-oxo-5-cholestenoic acid;Cholest-5-en-26-oic acid, 3-hydroxy-7-oxo-, (3β,25R)-
- CBNumber:
- CB94742471
- Molecular Formula:
- C27H42O4
- Molecular Weight:
- 430.63
- MDL Number:
- MFCD19704918
- MOL File:
- 1246298-64-5.mol
3Β-HYDROXY-7-OXO-5-CHOLESTENOIC ACID Chemical Properties,Uses,Production
Uses
3?-Hydroxy-7-oxo-5-cholestenoic acid is used in the study of mammalian pathological biochemistry for defective cholesterol metabolism in amyotrophic lateral schlerosis.
Biological Activity
3β-hydroxy-7-oxocholest-5-en-26-oic acid (3βH,7O-CA) acts as a ligand for liver X receptors (LXR) and activates them at micromolar concentration. 3βH,7O-CA favors the islet-1+ cells synthesis and islet-1–GFP expression. 3βH,7O-CA also mediates oculomotor neurons maturation and its conversion to 3β,7β-dihydroxycholest-5-en-(25S)26-oic acid (3β,7β-diHCA) is catalyzed by the enzyme hydroxysteroid 11-β dehydrogenase.
3Β-HYDROXY-7-OXO-5-CHOLESTENOIC ACID Preparation Products And Raw materials
Raw materials
Preparation Products
3Β-HYDROXY-7-OXO-5-CHOLESTENOIC ACID Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Creative Enzymes | 1-516-855-7709 | info@creative-enzymes.com | United States | 8748 | 58 |
| SHANGHAI ZZBIO CO., LTD. | 15102117276 19921389125 | tech@zzbioco.com | China | 12064 | 58 |
| Merck KGaA | 21-20338288 | ordercn@merckgroup.com | China | 6394 | 58 |
| Guangzhou Lucheng Biotechnology Co., Ltd. | 16620452357 | CHINA | 0 | 58 | |
| Guangdong Zijinggang Technology Co., Ltd. | 13128698830 | CHINA | 0 | 58 |
| Supplier | Advantage |
|---|---|
| Creative Enzymes | 58 |
| SHANGHAI ZZBIO CO., LTD. | 58 |
| Merck KGaA | 58 |
| Guangzhou Lucheng Biotechnology Co., Ltd. | 58 |
| Guangdong Zijinggang Technology Co., Ltd. | 58 |
