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ChemicalBook >> CAS DataBase List >>E3 Ligase Ligand-Linker Conjugates 22

E3 Ligase Ligand-Linker Conjugates 22

CAS No.
2225940-52-1
Chemical Name:
E3 Ligase Ligand-Linker Conjugates 22
Synonyms
Pomalidomide-PEG4-C2-NH2;Cereblon Ligand-Linker Conjugates 8;E3 Ligase Ligand-Linker Conjugates 22;Pomalidomide-PEG4-C2-NH2, 10 mM in DMSO;4-((14-amino-3,6,9,12-tetraoxatetradecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione;inhibit,PomalidomidePEG4C2NH2,E3 Ligase Ligand-Linker Conjugates,Inhibitor,Pomalidomide PEG4 C2 NH2;1H-Isoindole-1,3(2H)-dione, 4-[(14-amino-3,6,9,12-tetraoxatetradec-1-yl)amino]-2-(2,6-dioxo-3-piperidinyl)-;4-(15-amino-4,7,10,13-tetraoxa-1-azapentadecan-1-yl)-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione;4-((14-Amino-3,6,9,12-tetraoxatetradecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione?, Pomalidomide-PEG4-C2-NH2
CBNumber:
CB74797048
Molecular Formula:
C23H32N4O8
Molecular Weight:
492.52
MDL Number:
MFCD31715437
MOL File:
2225940-52-1.mol
Last updated:2025-07-16 20:18:59

E3 Ligase Ligand-Linker Conjugates 22 Properties

Boiling point 714.3±60.0 °C(Predicted)
Density 1.335±0.06 g/cm3(Predicted)
pka 10.74±0.40(Predicted)
form Solid
color Light yellow to yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

E3 Ligase Ligand-Linker Conjugates 22 price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biorbyt Ltd orb572875 E3 Ligase Ligand-Linker Conjugates 22 >97% 2225940-52-1 100mg $838.1 2021-12-16 Buy
Biorbyt Ltd orb572875 E3 Ligase Ligand-Linker Conjugates 22 >97% 2225940-52-1 250mg $1654.1 2021-12-16 Buy
Biorbyt Ltd orb572875 E3 Ligase Ligand-Linker Conjugates 22 >97% 2225940-52-1 1g $3282.7 2021-12-16 Buy
DC Chemicals DC12141 E3LigaseLigand-LinkerConjugates22 >97% 2225940-52-1 1g $2200 2021-12-16 Buy
DC Chemicals DC12141 E3LigaseLigand-LinkerConjugates22 >97% 2225940-52-1 250mg $1100 2021-12-16 Buy
Product number Packaging Price Buy
orb572875 100mg $838.1 Buy
orb572875 250mg $1654.1 Buy
orb572875 1g $3282.7 Buy
DC12141 1g $2200 Buy
DC12141 250mg $1100 Buy

E3 Ligase Ligand-Linker Conjugates 22 Chemical Properties,Uses,Production

Uses

Pomalidomide-PEG4-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Pomalidomide based cereblon ligand and 4-unit PEG linker used in PROTAC technology.

IC 50

Cereblon

References

[1] Jian Jin, et al. Compositions and methods for treating ezh2-mediated cancer. WO2018081530A1.

E3 Ligase Ligand-Linker Conjugates 22 Preparation Products And Raw materials

Raw materials

Preparation Products

E3 Ligase Ligand-Linker Conjugates 22 Suppliers

Global( 22)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32376 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42056 58
Aikon International Limited 025-58859352 18068836627 dt3@aikonchem.com China 15494 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1603 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11218 58
Nanjing Bestfluorodrug Pharmaceutical Technology CO.,LTD 025-86755008 17751752005 hszhang@bestfluorodrug.com China 2358 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 39994 58
QUALITY CONTROL SOLUTIONS LTD. 0755-66853366; 13670046396 ORDERS@QCSRM.COM China 24342 58
Xi'an Qiyue Biotechnology Co., Ltd. 400-400-6966-012-012 17778955912 2957605606@qq.com China 2535 58

View Lastest Price from E3 Ligase Ligand-Linker Conjugates 22 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pomalidomide-PEG4-C2-NH2 pictures 2025-07-16 Pomalidomide-PEG4-C2-NH2
2225940-52-1
US $30.00-68.00 / mg 95.73% 10g TargetMol Chemicals Inc.
E3 Ligase Ligand-Linker Conjugates 22 Pomalidomide-PEG4-C2-NH2 Cereblon Ligand-Linker Conjugates 8 1H-Isoindole-1,3(2H)-dione, 4-[(14-amino-3,6,9,12-tetraoxatetradec-1-yl)amino]-2-(2,6-dioxo-3-piperidinyl)- 4-((14-amino-3,6,9,12-tetraoxatetradecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione inhibit,PomalidomidePEG4C2NH2,E3 Ligase Ligand-Linker Conjugates,Inhibitor,Pomalidomide PEG4 C2 NH2 4-(15-amino-4,7,10,13-tetraoxa-1-azapentadecan-1-yl)-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione 4-((14-Amino-3,6,9,12-tetraoxatetradecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione?, Pomalidomide-PEG4-C2-NH2 Pomalidomide-PEG4-C2-NH2, 10 mM in DMSO 2225940-52-1 peg