Pomalidomide-PEG1-azide
- CAS No.
- 2133360-04-8
- Chemical Name:
- Pomalidomide-PEG1-azide
- Synonyms
- N3-PEG1-CH2CO-Poma;Pomalidomide-PEG1-azide;Pomalidomide-NH-CO-PEG1-N3;2-(2-Azidoethoxy)-N-[2-(2,6-dioxo-3-piperidyl)-1,3-dioxoisoindolin-4-yl]acetamide;Acetamide, 2-(2-azidoethoxy)-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-;2-(2-Azidoethoxy)-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)acetamide?, Pomalidomide-PEG1-azide;Pomalidomide-PEG1-azide/Acetamide,2-(2-azidoethoxy)-N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-
- CBNumber:
- CB24813989
- Molecular Formula:
- C17H16N6O6
- Molecular Weight:
- 400.35
- MDL Number:
- MFCD32198602
- MOL File:
- 2133360-04-8.mol
Pomalidomide-PEG1-azide Chemical Properties,Uses,Production
Uses
Protein degrader builiding block Pomalidomide-PEG1-azide enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant azide for click chemistry with a target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation When used with other protein degrader building blocks with a pendant azide group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.
reaction suitability
reaction type: click chemistry
reagent type: ligand-linker conjugate
Pomalidomide-PEG1-azide Preparation Products And Raw materials
Raw materials
Preparation Products
Pomalidomide-PEG1-azide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 32359 | 58 |
| Xian confluore Biological Technology Co., Ltd. | +86-15680926068 | 1924344760@confluore.cn | China | 2997 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 57505 | 58 | |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51395 | 80 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 021-61312847; 18021002903 | 3008007409@qq.com | China | 71826 | 60 |
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4841 | 58 |
| Jilin Province Woda Biotechnology Co., Ltd. | 13504435624 | 1927928688@qq.com | China | 1596 | 58 |
| Shaanxi borno biotechnology co., LTD | +86-13759708231 | asherw9@hotmail.com | China | 2373 | 58 |
| Shanghai Haohong Pharmaceutical Co., Ltd. | 400-8210725 4008210725 | malulu@leyan.com | China | 55000 | 58 |
View Lastest Price from Pomalidomide-PEG1-azide manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-06-07 | Pomalidomide-NH-CO-PEG1-N3
2133360-04-8
|
US $0.00 / mg | 100mg | >99.00% | 100mg | Xian confluore Biological Technology Co., Ltd. |
-
- Pomalidomide-NH-CO-PEG1-N3
2133360-04-8
- US $0.00 / mg
- >99.00%
- Xian confluore Biological Technology Co., Ltd.
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