Dexelvucitabine
- CAS No.
- 134379-77-4
- Chemical Name:
- Dexelvucitabine
- Synonyms
- RVT;YZ 817;D-D-4FC;DPC-817;Reverset;RA 131423;INCB 8721;beta-D-D-4FC;Dexelvucitabine;Dexelvucitabine, 10 mM in DMSO
- CBNumber:
- CB71178464
- Molecular Formula:
- C9H10FN3O3
- Molecular Weight:
- 227.19
- MDL Number:
- MFCD09954118
- MOL File:
- 134379-77-4.mol
- MSDS File:
- SDS
| Boiling point | 394.9±52.0 °C(Predicted) |
|---|---|
| Density | 1.66±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO:0.0(Max Conc. mg/mL);0.0(Max Conc. mM) |
| form | Solid |
| pka | 14.28±0.10(Predicted) |
| color | White to off-white |
| FDA UNII | KU8SPJ271W |
Dexelvucitabine price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth Carbosynth | NF58422 | 5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-b-D-arabinofuranosyl)-cytosine | 134379-77-4 | 25mg | $225 | 2021-12-16 | Buy |
| Biosynth Carbosynth | NF58422 | 5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-b-D-arabinofuranosyl)-cytosine | 134379-77-4 | 50mg | $363 | 2021-12-16 | Buy |
| Biosynth Carbosynth | NF58422 | 5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-b-D-arabinofuranosyl)-cytosine | 134379-77-4 | 100mg | $580 | 2021-12-16 | Buy |
| Biosynth Carbosynth | NF58422 | 5-Fluoro-1-(2',3'-dideoxy-2',3'-didehydro-b-D-arabinofuranosyl)-cytosine | 134379-77-4 | 250mg | $880 | 2021-12-16 | Buy |
| AK Scientific | 3713CA | Dexelvucitabine | 134379-77-4 | 250mg | $1238 | 2021-12-16 | Buy |
Dexelvucitabine Chemical Properties,Uses,Production
Uses
Treatment of HIV-1 and HIV-2 infection.
Uses
Dexelvucitabine is a nucleoside reverse transcriptase inhibitor (NRTI) which had the potential to inhibit HIV-1 replication. The drug was discontinued due to evidence that it causes damage to the pancreas.
brand name
Reverset (Incyte).
in vivo
Dexelvucitabine (Reverset; d-d4FC; 33.3 mg/kg by i.v. or p.o.) has distribution and elimination half-lives (t1/2α?and?t1/2β, respectively) of 0.7 and 3.6 h in monkeys, respectively. The Cmax ranges from 21.1 to 47.5 μM[2].
Dexelvucitabine has a favorable pharmacokinetic profile with a long half-life (4.71 and 10.75 h after administration by the intravenous [i.v.] and oral [p.o.] routes, respectively)?in woodchucks[2].
IC 50
HIV-1
Dexelvucitabine Preparation Products And Raw materials
Raw materials
Preparation Products
Dexelvucitabine Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19552 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5745 | 58 |
| TargetMol Chemicals Inc. | +17819995354 | marketing@targetmol.com | United States | 32364 | 58 |
| NewCan Biotech Limited | +86-0571-86912261 +8613735419629 | sales@newcanbio.com | China | 9985 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| LGM Pharma | 1-(800)-881-8210 | inquiries@lgmpharma.com | United States | 2123 | 70 |
| Shanghai Fuhe Chemistry Technology Co., Ltd. | 0086-21-67651709 | cfx759@hotmail.com | China | 410 | 57 |
| T&W GROUP | 021-61551611 13296011611 | contact@trustwe.com | China | 9895 | 58 |