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ChemicalBook >> CAS DataBase List >>MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH

MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH

CAS No.
189696-20-6
Chemical Name:
MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH
Synonyms
MCA-DEVDAPK (DNP);MCA-DEVDAPK(DNP)-OH;CASPASE-3 SUBSTRATE (MCA);CPP32 Fluorogenic Substrate III;CASPASE-3 SUBSTRATE III, FLUOROGENIC;MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP);MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH;MCA-Asp-Glu-Val-Asp-Ala-Pro-Lys(Dnp)-COOH;7-methoxycoumarin-4-acetyl-asp-glu-*val-asp-ala-P;MCA-DEVDAPK(DNP)-OH;CPP32 FLUOROGENIC SUBSTRATE III
CBNumber:
CB6715311
Molecular Formula:
C50H62N10O22
Molecular Weight:
1155.08
MDL Number:
MFCD00798785
MOL File:
189696-20-6.mol
Last updated:2025-08-05 17:23:12

MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH Properties

Boiling point 1561.2±65.0 °C(Predicted)
Density 1.455±0.06 g/cm3(Predicted)
storage temp. −20°C
solubility Formic Acid: 1 mg/ml
form Lyophilized powder
pka 3.67±0.21(Predicted)

SAFETY

Risk and Safety Statements

WGK Germany  3

MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH price More Price(10)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich M1169 7-Methoxycoumarin-4-acetyl-Asp-Glu-Val-Asp-Ala-Pro-(2,4-dinitrophenyl)Lys 189696-20-6 0.5mg $361 2023-01-07 Buy
Cayman Chemical 24563 Mca-DEVDAPK(Dnp)-OH ≥95% 189696-20-6 500μg $128 2024-03-01 Buy
Cayman Chemical 24563 Mca-DEVDAPK(Dnp)-OH ≥95% 189696-20-6 1mg $243 2024-03-01 Buy
AK Scientific 6266DU (2S)-2-[[(2S)-1-[(2S)-2-[[(2S)-3-Carboxy-2-[[(2S)-2-[[(2S)-4-carboxy-2-[[(2S)-3-carboxy-2-[[2-(7-methoxy-2-oxochromen-4-yl)acetyl]amino]propanoyl]amino]butanoyl]amino]-3-methylbutanoyl]amino]propanoyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-6-(2,4-dinitroanilino)hexanoicacid 189696-20-6 1mg $348 2021-12-16 Buy
American Custom Chemicals Corporation CHM0115377 7-METHOXYCOUMARIN-4-ACETYL-ASP-GLU-VAL-ASP-ALA-PRO-(2,4-DINITROPHENYL)LYS 95.00% 189696-20-6 0.5MG $768.65 2021-12-16 Buy
Product number Packaging Price Buy
M1169 0.5mg $361 Buy
24563 500μg $128 Buy
24563 1mg $243 Buy
6266DU 1mg $348 Buy
CHM0115377 0.5MG $768.65 Buy

MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH Chemical Properties,Uses,Production

Description

Mca-DEVDAPK(Dnp)-OH is a fluorogenic substrate for caspase-3. It is cleaved by caspase-3 to release the fluorescent moiety 7-methoxycoumarin-4-acetyl (Mca), which can be used to quantify caspase-3 activity.

Uses

Mca-DEVDAP-K(Dnp)-OH is a fluorogenic substrate for caspase-3[1].

IC 50

Caspase-3

References

[1] Fertig Georg. Method for the detection of the apoptosis activated cysteine protease Caspase 3 by specific antibody-binding and fluorescence enzyme assay. EP0955377A1

Sequene

Mca-Asp-Glu-Val-Asp-Ala-Pro-Lys(Dnp)-OH

MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH Preparation Products And Raw materials

Raw materials

Preparation Products

MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH Suppliers

Global( 30)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32376 58
Chengdu Youngshe Chemical Co., Ltd. 		+8618108235634 Cecilia@youngshechem.com China 2345 58
DAYANG CHEM (HANGZHOU) CO.,LTD 		+86-88938639 +86-17705817739 info@dycnchem.com China 53900 58
GL Biochem (Shanghai) Ltd 21-61263452 13641803416 ymbetter@glbiochem.com China 9981 64
Shanghai Hanhong Scientific Co.,Ltd. 021-54306202 13764082696 info@hanhongsci.com China 42953 64
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15402 60
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9803 58
Nanjing Leon Biological Technology Co., Ltd. 17705183659 sales@njleonbiotech.com China 5501 55
Nanjing Peptide Biotech Ltd. 025-58361106-805 15951641583 zhao.xu@njpeptide.com China 9980 55
Nanjing Meihao Pharmaceutical Technology Co., Ltd. meitaochem@126.com meitaochem@126.com China 19103 58

View Lastest Price from MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Mca-DEVDAPK(Dnp)-OH pictures 2024-11-19 Mca-DEVDAPK(Dnp)-OH
189696-20-6
 US $595.00 / mg 10g TargetMol Chemicals Inc.
MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP) MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS(DNP)-OH MCA-DEVDAPK (DNP) MCA-DEVDAPK(DNP)-OH CASPASE-3 SUBSTRATE III, FLUOROGENIC CASPASE-3 SUBSTRATE (MCA) 7-METHOXYCOUMARIN-4-ACETYL-ASP-GLU-VAL-ASP-ALA-PRO-(2,4-DINITROPHENYL)-LYS 7-methoxycoumarin-4-acetyl-asp-glu-*val-asp-ala-P 7-METHOXYCOUMARIN-4-ACETYL-ASP-GLU-*VAL- ASP-ALA-PRO MCA-ASP-GLU-VAL-ASP-ALA-PRO-LYS: DNP[MCA-DEVDAP-K: DNP] CPP32 Fluorogenic Substrate III MCA-DEVDAPK(DNP)-OH;CPP32 FLUOROGENIC SUBSTRATE III L-Lysine,N-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-α-aspartyl-L-α-glutamyl-L-valyl-L-α-aspartyl-L-alanyl-L-prolyl-N6-(2,4-dinitrophenyl)- L-Lysine, N-[(7-methoxy-2-oxo-2H-1-benzopyran-4-yl)acetyl]-L-α-aspartyl-L-α-glutamyl-L-valyl-L-α-aspartyl-L-alanyl-L-prolyl-N6-(2,4-dinitrophenyl)- (9CI) MCA-Asp-Glu-Val-Asp-Ala-Pro-Lys(Dnp)-COOH 189696-20-6 C50H62N10O22 Substrates BioChemical Caspase 3 Caspases Cell Biology Cell Signaling and Neuroscience Apoptosis and Cell Cycle Caspase 3 Caspase 3Caspase Inhibitors and Substrates Caspase Substrates Caspases Substrates