2-AMINO-5-FLUOROBENZAMIDE
- CAS No.
- 63069-49-8
- Chemical Name:
- 2-AMINO-5-FLUOROBENZAMIDE
- Synonyms
- 5-FLUOROANTHRANILAMIDE;2-AMINO-5-FLUOROBENZAMIDE;Benzamide, 2-amino-5-fluoro-;2-Amino-5-fluorobenzamide97%;2-Amino-5-fluorobenzamide 97%;2-Amino-5-fluorobenzamide, >=98%;2-Carbamoyl-4-fluoroaniline, 5-Fluoroanthranilamide
- CBNumber:
- CB6416306
- Molecular Formula:
- C7H7FN2O
- Molecular Weight:
- 154.14
- MDL Number:
- MFCD03428522
- MOL File:
- 63069-49-8.mol
- MSDS File:
- SDS
| Melting point | 143-148℃ |
|---|---|
| Boiling point | 259.3±25.0 °C(Predicted) |
| Density | 1.344±0.06 g/cm3(Predicted) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| pka | 15.23±0.50(Predicted) |
| form | Crystalline |
| color | Off-white |
| InChI | InChI=1S/C7H7FN2O/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H,9H2,(H2,10,11) |
| InChIKey | RHJMYIPLYKQZJM-UHFFFAOYSA-N |
| SMILES | C(N)(=O)C1=CC(F)=CC=C1N |
| CAS DataBase Reference | 63069-49-8(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36/37/39 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 2924297099 | |||||||||
| NFPA 704 |
|
2-AMINO-5-FLUOROBENZAMIDE price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TCI Chemical | A3181 | 2-Amino-5-fluorobenzamide >98.0%(HPLC) | 63069-49-8 | 1g | $64 | 2025-07-31 | Buy |
| TRC | A617560 | 2-Amino-5-fluoro-benzamide | 63069-49-8 | 1g | $55 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FA70235 | 2-Amino-5-fluorobenzamide | 63069-49-8 | 50g | $250 | 2021-12-16 | Buy |
| AK Scientific | L183 | 2-Amino-5-fluorobenzamide | 63069-49-8 | 25g | $303 | 2021-12-16 | Buy |
| AK Scientific | L183 | 2-Amino-5-fluorobenzamide | 63069-49-8 | 50g | $387 | 2021-12-16 | Buy |
2-AMINO-5-FLUOROBENZAMIDE Chemical Properties,Uses,Production
Uses
2-Amino-5-fluoro-benzamide?is a useful reagent to prepare various quinazolinones including the enantioselective synthesis of fluoro-dihydroquinazolones and -benzooxazinones.
Synthesis
446-08-2
63069-49-8
General procedure for the synthesis of 2-amino-5-fluorobenzamide from 2-amino-5-fluorobenzoic acid: A solution of 2-amino-5-fluorobenzoic acid (3 g, 19.34 mmol) in tetrahydrofuran (64.5 mL) was added to a round-bottomed flask, and a toluene solution of 20% phosgene (11.2 mL, 21.3 mmol) was slowly added dropwise. The reaction mixture was stirred at room temperature for 18 h. The mixture was subsequently cooled to 0 °C and concentrated ammonium hydroxide solution (27.9 mL, 193 mmol) was carefully added. The mixture was gradually warmed to room temperature and stirring was continued for 1 hour. After completion of the reaction, the organic phase was diluted with ethyl acetate, washed sequentially with aqueous dipotassium hydrogen phosphate and saturated brine, dried over anhydrous sodium sulfate and concentrated to give the white solid product 2-amino-5-fluorobenzamide (2.46 g, 82% yield). Mass spectral data: M(C7H7FN2O) = 154.14, (M + H - NH3)+ = 138.
References
[1] Patent: US2008/182852, 2008, A1. Location in patent: Page/Page column 28
[2] Molecules, 2017, vol. 22, # 2,
[3] Patent: WO2018/125961, 2018, A1. Location in patent: Page/Page column 77
[4] Journal of Medicinal Chemistry, 2000, vol. 43, # 23, p. 4479 - 4487
[5] Patent: US6479499, 2002, B1
2-AMINO-5-FLUOROBENZAMIDE Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3889 | 58 |
| Capot Chemical Co.,Ltd. | +8613336195806 | sales@capot.com | China | 29731 | 60 |
| Changzhou Ansciep Chemical Co., Ltd. | +86 519 86305871 | sales@ansciepchem.com | CHINA | 4241 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49733 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29804 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-87569262 +86-15003564040 | 1087@dideu.com | China | 3299 | 58 |
| Fuxin Pharmaceutical | +86-021-021-50872116 +8613122107989 | contact@fuxinpharm.com | China | 10035 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Win-Win chemical CO., Limited | +86-0086-577-64498589 +86-15355981851 | sales@win-winchemical.com | China | 14459 | 58 |
View Lastest Price from 2-AMINO-5-FLUOROBENZAMIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-07-25 | 2-AMINO-5-FLUOROBENZAMIDE
63069-49-8
|
US $0.00-0.00 / KG | 1KG | 98.0% | 10000KGS | Shaanxi Dideu New Materials Co. Ltd | |
 |
2024-08-05 | 2-AMINO-5-FLUOROBENZAMIDE
63069-49-8
|
US $0.10 / KG | 1KG | 98.0% | 10 | Shaanxi Dideu Medichem Co. Ltd | |
 |
2019-12-24 | 2-AMINO-5-FLUOROBENZAMIDE
63069-49-8
|
US $1.00 / KG | 1KG | 99% | 1000KGS | Career Henan Chemical Co |
-
- 2-AMINO-5-FLUOROBENZAMIDE
63069-49-8
- US $0.00-0.00 / KG
- 98.0%
- Shaanxi Dideu New Materials Co. Ltd
-
- 2-AMINO-5-FLUOROBENZAMIDE
63069-49-8
- US $0.10 / KG
- 98.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- 2-AMINO-5-FLUOROBENZAMIDE
63069-49-8
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
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