ChemicalBook >> CAS DataBase List >>Sarolaner
Sarolaner
- CAS No.
- 1398609-39-6
- Chemical Name:
- Sarolaner
- Synonyms
- Saiolana;Saoranna;PF6450567;Sarolaner;Sharolana;PF 6450567;PF 6450567;PF6450567;Sarolaner(PF-6450567);Sarolaner, 10 mM in DMSO;Sarolaner (Synonyms: PF-6450567)
- CBNumber:
- CB53344764
- Molecular Formula:
- C23H18Cl2F4N2O5S
- Molecular Weight:
- 581.36
- MDL Number:
- MFCD28963963
- MOL File:
- 1398609-39-6.mol
Last updated:2025-07-08 16:52:38
| Boiling point | 722.7±70.0 °C(Predicted) |
|---|---|
| Density | 1.65±0.1 g/cm3(Predicted) |
| storage temp. | Store at 4°C, sealed storage, away from moisture |
| solubility | DMF: Slightly soluble; DMSO: Slightly soluble; Ethanol: Slightly soluble |
| form | A solid |
| pka | -0.93±0.20(Predicted) |
| color | White to off-white |
| InChIKey | FLEFKKUZMDEUIP-QFIPXVFZSA-N |
| SMILES | C(=O)(N1CC2(C3=C(C=C(C4C[C@](C5=CC(Cl)=C(F)C(Cl)=C5)(C(F)(F)F)ON=4)C=C3)CO2)C1)CS(C)(=O)=O |
| FDA UNII | DM113FTW7F |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H400-H302-H410 | |||||||||
| Precautionary statements | P264-P270-P301+P312-P330-P501-P273-P391-P501-P273-P391-P501 | |||||||||
| NFPA 704 |
|
Sarolaner price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | S141670 | Sarolaner | 1398609-39-6 | 1mg | $415 | 2021-12-16 | Buy |
| ChemScene | CS-0012328 | Sarolaner 99.47% | 1398609-39-6 | 50mg | $850 | 2021-12-16 | Buy |
| ChemScene | CS-0012328 | Sarolaner 99.47% | 1398609-39-6 | 100mg | $1500 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb573185 | Sarolaner(PF-6450567) >98% | 1398609-39-6 | 100mg | $1654.1 | 2021-12-16 | Buy |
| Biorbyt Ltd | orb573185 | Sarolaner(PF-6450567) >98% | 1398609-39-6 | 250mg | $3136.5 | 2021-12-16 | Buy |
Sarolaner Chemical Properties,Uses,Production
Uses
Sarolaner is used in the making of formulations for the control of ticks in cats, and flea infestations in dogs. A parasiiticide.
in vivo
Sarolaner (2.5 mg/kg; p.o. once) shows 100% efficacious against R. sanguineus and D. reticulatus[1]. Sarolaner (1.25- 5 mg/kg; p.o. once) effectively against I. ricinus[1].
| Animal Model: | Dog infested with R. sanguineus and D. reticulatus[1] |
| Dosage: | 2.5 mg/kg |
| Administration: | Oral gavage; 2.5 mg/kg once |
| Result: | Exibited 100% efficacy against R. sanguineus at 48 hours after treatment and also exhibited 98.0% efficacy againstD. reticulatus. |
| Animal Model: | Dog infested with I. ricinus[1] |
| Dosage: | 1.25, 2.5 and 5 mg/kg |
| Administration: | Oral gavage; 1.25, 2.5 and 5 mg/kg once |
| Result: | Exibited 100% efficacy against I. ricinus at all doses until 7 days, and provided over 99.3% reduction against subsequent re-infestations until 57 days at dose of 5.0 and 2.5 mg/kg. |
Synthesis of Sarolaner from METHANESULFONYLACETIC ACID and Ethanamine, N-[(3,5-dichlorophenyl)methylene]-2,2-diethoxy-
Sarolaner Preparation Products And Raw materials
Global( 109)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3889 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86-13288715578 | sales@hbmojin.com | China | 12745 | 58 |
| Hebei Dangtong Import and export Co LTD | +86-86-4001020630 +8619831957301 | admin@hbdangtong.com | China | 1000 | 58 |
| shandong perfect biotechnology co.ltd | +86-53169958659 +86-13153181156 | sales@sdperfect.com | China | 294 | 58 |
| Wuhan Haorong Biotechnology Co.,ltd | +8618565342920 | sales@chembj.net | China | 311 | 58 |
| Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 | xinshengkeji@xsmaterial.com | China | 1085 | 58 |
| hebei hongtan Biotechnology Co., Ltd | +852-6619 3215 +86-17731935328 | sales03@chemcn.cn | China | 970 | 58 |
| Hebei Ganmiao New material Technology Co., LTD | +86-17332992504 | sales8@hbganmiao.com | China | 300 | 58 |
| Hebei Junhua Import and Export Co., LTD | +86-18503288844 | junhua1@hb-junhua.com | China | 958 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29855 | 58 |
View Lastest Price from Sarolaner manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-07-18 | Sarolaner
1398609-39-6
|
US $1.00 / kg | 1kg | 99% | 10000 | Wuhan Haorong Biotechnology Co.,Ltd | |
 |
2025-07-18 | *Sarolaner
1398609-39-6
|
US $0.00-0.00 / kg | 1kg | 0.99 | 2500kg | Wuhan Biocar Pharmacy CO.,Ltd. | |
 |
2025-07-18 | Sarolaner
1398609-39-6
|
US $0.00 / kg | 1kg | 98% | 1000 | Hebei Junhua Import and Export Co., LTD |
-
- Sarolaner
1398609-39-6
- US $1.00 / kg
- 99%
- Wuhan Haorong Biotechnology Co.,Ltd
-
- *Sarolaner
1398609-39-6
- US $0.00-0.00 / kg
- 0.99
- Wuhan Biocar Pharmacy CO.,Ltd.
-
- Sarolaner
1398609-39-6
- US $0.00 / kg
- 98%
- Hebei Junhua Import and Export Co., LTD
Sarolaner
1-[6-[(5S)-5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4H-1,2-oxazol-3-yl]spiro[1H-2-benzofuran-3,3'-azetidine]-1'-yl]-2-methylsulfonylethanone
PF 6450567;PF6450567
PF6450567
PF 6450567
Sarolaner(PF-6450567)
(S)-1-(5'-(5-(3,5-Dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethanone
Ethanone, 1-[5'-[(5S)-5-(3,5-dichloro-4-fluorophenyl)-4,5-dihydro-5-(trifluoromethyl)-3-isoxazolyl]spiro[azetidine-3,1'(3'H)-isobenzofuran]-1-yl]-2-(methylsulfonyl)-
dog,Sarolaner,Parasite,PF 6450567,flea,Inhibitor,oral,inhibit,isoxazoline,tick,PF6450567
(S)-1-(5'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethan-1-one
Sarolaner, 10 mM in DMSO
Sarolaner (Synonyms: PF-6450567)
Saiolana
Saoranna
Sharolana
(S)-1-(5'-(5-(3,5-dichloro-4-fluorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl)-3'H-spiro[azetidine-3,1'-isobenzofuran]-1-yl)-2-(methylsulfonyl)ethan-1-one
Sarolaner 100 μg/mL in Acetonitrile
1398609-39-6
C23H18Cl2F4N2O5S