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ChemicalBook >> CAS DataBase List >>BIOTIN DISULFIDE N-HYDROXY-SUCCINIMIDE ESTER

BIOTIN DISULFIDE N-HYDROXY-SUCCINIMIDE ESTER

CAS No.
142439-92-7
Chemical Name:
BIOTIN DISULFIDE N-HYDROXY-SUCCINIMIDE ESTER
Synonyms
BIOTIN DSHSE;NHS-SS-11-Biotin;(+)-Biotin-SS-NHS;Biotin-bisamido-SS-NHS;Biotin-bisamido-SS-NHS ester;BIOTIN DISULFIDE N-HYDROXY-SUCCINIMIDE ESTER;SucciniMidyl 2-(biotinaMido)-ethyl-1,3' -dithiopropionate;Succinimidyl 3-[3-[2-(biotinamido)ethyl]amino-3-oxopropyl]dithio]propionate;[2-(BIOTINAMIDO)ETHYLAMIDO]-3,3'-DITHIODIPROPIONIC ACID N-HYDROXYSUCCINIMIDE ESTER;(3aS,4S,6aR)-N-[2-[[3-[[3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl]dithio]-1-oxopropyl]amino]ethyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide
CBNumber:
CB3715390
Molecular Formula:
C22H33N5O7S3
Molecular Weight:
575.72
MDL Number:
MFCD00466919
MOL File:
142439-92-7.mol
Last updated:2025-04-17 18:22:24

BIOTIN DISULFIDE N-HYDROXY-SUCCINIMIDE ESTER Properties

Melting point 129-131°C
Density 1.43
storage temp. −20°C
solubility DMF: 50 mg/mL
pka 13.90±0.40(Predicted)
form powder
UNSPSC Code 12352203
NACRES NA.46

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Danger
Hazard statements  H360D
Precautionary statements  P201-P202-P280-P308+P313-P405-P501
Hazard Codes  T
Risk Statements  61
Safety Statements  53-23-36/37/39-45
WGK Germany  1
HS Code  29349990

BIOTIN DISULFIDE N-HYDROXY-SUCCINIMIDE ESTER price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich B4531 Biotin disulfide N-hydroxysuccinimide ester >98%, powder 142439-92-7 10mg $147.2 2024-03-01 Buy
Sigma-Aldrich B4531 Biotin disulfide N-hydroxysuccinimide ester >98%, powder 142439-92-7 100mg $2030 2024-03-01 Buy
TRC N394000 NHSSSBiotin 142439-92-7 1g $925 2021-12-16 Buy
Biosynth Carbosynth FB52737 (2-[Biotinamido]ethylamido)-3,3'-dithiodipropionic acid N-hydroxysuccinimide ester 142439-92-7 5mg $50 2021-12-16 Buy
Biosynth Carbosynth FB52737 (2-[Biotinamido]ethylamido)-3,3'-dithiodipropionic acid N-hydroxysuccinimide ester 142439-92-7 10mg $75 2021-12-16 Buy
Product number Packaging Price Buy
B4531 10mg $147.2 Buy
B4531 100mg $2030 Buy
N394000 1g $925 Buy
FB52737 5mg $50 Buy
FB52737 10mg $75 Buy

BIOTIN DISULFIDE N-HYDROXY-SUCCINIMIDE ESTER Chemical Properties,Uses,Production

Description

Biotin-bisamido-SS-NHS is a cleavable reagent which can efficiently introduce a biotin moiety to amine-containing biomolecules. The cross-bridge and extended spacer arm are helpful in minimizing steric hindrance involved with the binding to avidin or streptavidin probes. This biotin compound is membrane-permeable and useful for intracellular labeling. The disulfide bond in this linker can be cleaved using reducing agents such as DTT, BME and TCEP to remove the biotin label.

Uses

NHS SS Biotin is a amine reactive biotinylation reagent that labels antibodies and other proteins and molecules that contain primary amines. NHS SS Biotin reacts efficiently with pirmary amino groups in alkaline buffers to form stable amide bonds. The disulfide bond in the spacer arm of NHS SS Biotin is also cleavable using reducing agents such as TCEP and DTT.

IC 50

Alkyl/ether

BIOTIN DISULFIDE N-HYDROXY-SUCCINIMIDE ESTER Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 60)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 33024 60
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49733 58
TargetMol Chemicals Inc. 		+17819995354 marketing@targetmol.com United States 32362 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30230 58
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203 info@chemextension.com China 42056 58
Xian confluore Biological Technology Co., Ltd. 		+86-15680926068 1924344760@confluore.cn China 2997 58
Aladdin Scientific 		tp@aladdinsci.com United States 52924 58
J & K SCIENTIFIC LTD. 18210857532 jkinfo@jkchemical.com China 96815 76
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32321 50
Tianjin heowns Biochemical Technology Co., Ltd. 400 638 7771 sales@heowns.com China 14435 57

View Lastest Price from BIOTIN DISULFIDE N-HYDROXY-SUCCINIMIDE ESTER manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Biotin-bisamido-SS-NHS ester pictures 2025-06-07 Biotin-bisamido-SS-NHS ester
142439-92-7
 US $0.00 / mg 50mg >95.00% 50mg Xian confluore Biological Technology Co., Ltd.

BIOTIN DISULFIDE N-HYDROXY-SUCCINIMIDE ESTER Spectrum

[2-(BIOTINAMIDO)ETHYLAMIDO]-3,3'-DITHIODIPROPIONIC ACID N-HYDROXYSUCCINIMIDE ESTER BIOTIN DISULFIDE N-HYDROXY-SUCCINIMIDE ESTER Succinimidyl 3-[3-[2-(biotinamido)ethyl]amino-3-oxopropyl]dithio]propionate (+)-Biotin-SS-NHS (3aS,4S,6aR)-N-[2-[[3-[[3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl]dithio]-1-oxopropyl]amino]ethyl]hexahydro-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide Biotin-bisamido-SS-NHS BIOTIN DSHSE SucciniMidyl 2-(biotinaMido)-ethyl-1,3' -dithiopropionate Biotin-bisamido-SS-NHS ester 1H-Thieno[3,4-d]imidazole-4-pentanamide, N-[2-[[3-[[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl]dithio]-1-oxopropyl]amino]ethyl]hexahydro-2-oxo-, (3aS,4S,6aR)- NHS-SS-11-Biotin 142439-92-7 C22H33N5O7S3 C19H28N4S3O6 C22H33N5S3O7 Protein Modification Proteomics and Protein Expression Proteomics Reagents for Biotinylating Amines BioChemical Biotinylation BiotinylationReagents Biotinylation Reagents